ID A0A087YC94_POEFO Unreviewed; 376 AA.
AC A0A087YC94;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Lysocardiolipin acyltransferase 1 {ECO:0000313|Ensembl:ENSPFOP00000015647.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000015647.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000015647.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000256|ARBA:ARBA00008655}.
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DR EMBL; AYCK01001372; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007576472.1; XM_007576410.2.
DR RefSeq; XP_016518400.1; XM_016662914.1.
DR AlphaFoldDB; A0A087YC94; -.
DR STRING; 48698.ENSPFOP00000015647; -.
DR Ensembl; ENSPFOT00000015669.2; ENSPFOP00000015647.2; ENSPFOG00000015567.2.
DR GeneID; 103154934; -.
DR KEGG; pfor:103154934; -.
DR CTD; 253558; -.
DR eggNOG; KOG1505; Eukaryota.
DR GeneTree; ENSGT00950000182836; -.
DR OMA; GTHAKKV; -.
DR OrthoDB; 2906776at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0001885; P:endothelial cell development; IEA:Ensembl.
DR GO; GO:0060217; P:hemangioblast cell differentiation; IEA:Ensembl.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd07990; LPLAT_LCLAT1-like; 1.
DR InterPro; IPR032098; Acyltransf_C.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10983; 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR10983:SF16; LYSOCARDIOLIPIN ACYLTRANSFERASE 1; 1.
DR Pfam; PF16076; Acyltransf_C; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 80..202
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 376 AA; 43573 MW; 61F37823B3E956C7 CRC64;
MAVSVRGLFF IMALFLGSFF GSIVMLGPVL PLMLLSPAWY RWLTDRIVAT WLTLPVSLLE
LVFGVKVVIT GDGFIPGERS VIIMNHRTRL DWMFLWCCLL RYSYLRLEKI CLKAALKALP
GFGWAMQVAC FVFIQRRWEM DKAHLENMLD YFCDIREPLQ LLLFPEGTDL TENTKAKSDA
FAAQNNLPKM EYVLHPRSTG FTFIVDKLRK GDNLDAVHDI TVAYPKNIPQ TERHLVLGEF
PREIHFHVRR YPVSLLPSSS TELESWCRER WAEKESRLRD FYSGQPRGFD RDGVARVPPC
KSELRVGLIK AASLVYWSGF IAFCFAGLWL WPSFRLYVLV MTVVFTVQQK LAGGLELIEM
ACHRYWKEKV QERKIQ
//
