ID A0A087YEY6_POEFO Unreviewed; 3562 AA.
AC A0A087YEY6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=CUB and Sushi multiple domains 1 {ECO:0000313|Ensembl:ENSPFOP00000016589.1};
GN Name=CSMD1 {ECO:0000313|Ensembl:ENSPFOP00000016589.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000016589.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000016589.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYCK01003682; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01003683; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01003684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01003685; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01003686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 48698.ENSPFOP00000016589; -.
DR Ensembl; ENSPFOT00000016611.1; ENSPFOP00000016589.1; ENSPFOG00000016334.1.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT00940000155701; -.
DR OMA; DLVNFTC; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 28.
DR CDD; cd00041; CUB; 13.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 28.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 13.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF4; PROTEIN BETA CHAIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 13.
DR Pfam; PF00084; Sushi; 28.
DR SMART; SM00032; CCP; 28.
DR SMART; SM00042; CUB; 13.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 28.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 13.
DR PROSITE; PS01180; CUB; 13.
DR PROSITE; PS50923; SUSHI; 28.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3486..3507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..79
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 83..187
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 320..381
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 384..495
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 498..555
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 557..666
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 669..731
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 733..841
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 846..903
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 905..1015
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1020..1079
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1081..1189
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1192..1252
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1254..1366
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1369..1429
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1431..1541
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1544..1605
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1607..1715
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1721..1782
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1784..1893
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1896..1955
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1957..2065
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2068..2127
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2129..2240
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2240..2301
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2303..2414
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2414..2476
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2478..2539
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2540..2605
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2606..2663
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2664..2721
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2722..2779
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2780..2842
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2843..2901
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2905..2963
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2967..3025
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3026..3085
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3086..3143
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3144..3201
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3208..3266
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3267..3326
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 526..553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 874..901
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1254..1281
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 2634..2661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2692..2719
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2750..2777
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2813..2840
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2872..2899
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2934..2961
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2996..3023
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3114..3141
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3172..3199
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3237..3264
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 3562 AA; 388976 MW; 26184AB69CAF673D CRC64;
FEVQNTSVSK SILVLPSHTC GTPGLIPNGI IHGSRYNMGD KIRYSCESGF VLEGHSTLTC
IVSPGSGAQW DFPSPFCRAE GACGGTLRGT AGSITSPGYP AEYDNNLDCT WSILAEPGDT
IALVFNDFLL EDKYDFLEIS GTEAPSIWLT GTTLPSPVIS NKNWLRIHFT SDSNHRRKGF
SAQYQVNLKM QVSIFKVSLN KHEYIFNSTL LKTSLPTLFD YSIFEVYIKL TDVLSRLVSF
TLSLFFLAIG LLLLPSLVKC SKWHPGGKEK WCRKKTYSNE SLISAVKKAI ELKSRGVKMM
PSKDSSHKNA VLSQSGLAGD VCPDPGVPEN GKRMGSVFQV GSSVQFSCDD SYVLHGSKSI
TCQRVTDTLA AWSDHRPICR TRTCGSNLRG PRGVITSPNY PVQYENNAHC VWVITAMDSD
KVIKLSFDEF DLERGYDTLT VGDGGKIGDT RRVLYVLTGT SVPDLIVSLS NQMWLHLQSD
DTIGSAGFKA IYEEINRGGC GDPGVPAFGR RSGDRFQHGD VLTFFCQSAF ELVGEKTITC
QHNNQWSGNK PSCVFSCFFN FTAPSGTVLS PNYPEEYGNN LNCVWLIISE PGSRIHLFFS
DFDLEPQFDW LVVKDEVGLS EATTFGTFSG KDVPSQIASN GHIMRLEFQS DHSNTGKGFN
ISYTTFGQNE CHDPGVPVNG QRYGDQFQLG SSVAFRCDQG FIRTQQGSDQ VTCIIQDGNV
VWSAAVPRCE APCGGHLTAP AGVVLSPGWP SFYKDSLNCQ WVIEAQKDHA VKIHFDKFQT
EVNYDTLEIR DGPSASSPLI GEYHGTQAPH FLISTSNFLF LLFTTDNSRS SAGFSIRYES
VRMESDSCLD PGIPVNGRRH GSSFSIGSHV SFACNPGYTL SDQEPIVCEQ SHQWSHALPS
CDALCGGYVF GKTGTILSPG FPDFYPNSLN CTWTIEVSHG KGVHLVFHTF HLEENHDYLS
IIEDGNFQAP VARLTGSVLP PSVKAGLYGN FSVQLRFISD FSMSYEGFNI TFSGSEYDLE
PCEDPGVPAF SRRMGFRFGV GDSLAFSCFH GYRLEGDSKI TCLGGGRRVW SNTLPRCIAE
CGASTLGPEG VLLSPNFPSS YDNNHECIYR ITTEKGKGIR LKAERFSLQD GDYLKVYDGE
NTTSRLLGNF TLDGMMGRVI NSTSNHLWME FNSNASGTDQ GFRLTYTSFD LVRCEEPGVP
SYGYKTQDDG HYANTFVLYS CNPGYTLHGS STLTCLSGDR RVWDKPLPSC IAECGGHITG
AVSGRILSPG YPAPYDNNLH CTWTIEADTG KTISLHFIVF DTEVGHDILR VWDGPSGSSD
GGILLKEWSG PALPEDSHST FNILTLQFDA DYFISKQGFS IQFSTTTATS CNDPGIPVNG
SRYGDSKEPG DSMTFQCDPG YQLQGQDTIT CVRMDNRFYW QPDPPTCMAT CGGNVSGPSG
VILSPNYPQP YPPGKECDWR IRVNPDFVIA LIFKSLSFNM EPSYDFLHIY EGEDSNGPLL
ASLQGNQAPE RIESSGNSLF LAFRSDASLG MSGFAIEYRE KPREACFDPG NIMNASRTGY
DYKLGSQVSY SCHHGYTIVG SETIMCVMGH DGKPVWDKAL PSCKAPCGGH YSGSEGVVLS
PNYPLNYTMR QMCSYHITVS PQFVVFGQFA VFQTAMNDSV ELFDGANDNA RLLSSLAGSH
SGETLPLATS NQIMLRFNAK SGQSAKGFHF VYQAVPRTSD SQCSSVPEPR YGRRIGSEFS
AGSVVRFECS PGYLLKGSSA IRCQAVPGAL AQWNSSTPTC IVPCSGNLTE RRGTILSPGY
PEPYPNALNC LWRIHVSEGA GIQIQVITFA TEHNWDSLEI YDGGDMTAPK LGSFSVGTTA
PALLNSTSNQ LLLHFQSDIS VVAAGFHLEY KTVGLTTCPE PVIPANGIKT GDRYMVNEVV
AFICEPGYTL QGHSHISCMP GTVRRWNYPP PLCIARCGGV LSEMSGVILS PGFPGNYPGN
LDCTWQITLP AGYGAHVQFQ NFSSEDNHDF LEVRAGPQHS SALIGQFTGS QIPPPLMSTT
HLTIIHFYSD HSENRPGFRL IYQAYQLQNC QDPSPFPNGD IIKSDYSAGQ SITFQCYSGY
VLIGHKVLTC LHGTNRKWNH PFPRCEAPCG YNVTAENGTI YSPQYPNEYP NSQDCSWLIS
VPHGHGVYIN FTLLQTEPVT DYIAVWDGPD TSSPQLGVFS GNTALESAYS SSSKVLVRFH
SDFSTGGFFI LNFHAAYRLK KCPPPPIVDN AEMIYEDEDF HIGDIVKYRC LPGYTLIGRA
ELMCKLNSHL LFEDPAPKCQ AQCPANEERF SSSGVILSPG FPGNYPNSQT CSWLLRMIPG
YTINIYVEMF HSEKQFDELE IFDGSSGQSP LLVALSGNHS SQLNFTSKTN QLYLRWSTDH
ATNKRGFKIR YSASYCSIND PPLNGGVVNR TKLHPGSRLQ FYCNHGYRLV GLSNATCRLD
SSGLYQWDAP APVCQAAVSC GIPQTPGNGS FHAYHYNVGS QVTYQCNYGY HLDPGAPVSA
VCLEDGSWSN TGSVPHCLPV HCPSIEGVLT EHMTYRLLIG RLAEFGSTVM LECSTGFYLG
VGHRTLRCLA NGTWEGSDDP ATCKIISCGE LPTPPFGTKL GTLTTFGATA IFMCNHGYTL
VGSHVRECGA DGLWSGAETN CLAGHCDSPD PIVNGHISGD GSSYRDTVVY QCMLGYRLIG
TSVRICQQDH RWSGTTPVCV PITCGHPGNP ANGRTNGSEF NLNDVVNFTC NKGYILSGNA
RAQCRLNGQW SNPLPVCKVV NCSDPGHVEN GVRQSGLRYP EVFSYGVTVA IHCKRGYYLL
GSAILTCQHS GLWDRPTPRC LAISCGDPGV PPNAAVSGTH SWTYGSVLQY SCLPGGVLVG
NSTRNCQEDG TWSGAPPYCT GASPGLCGDP GIPPHGTRLG GEEFKTKSLL RFSCEAGYNL
IGSAERTCLH NSSWSGTQPV CQQSSAVSCG NPGTPAHGRI VFNDGITFGS SVAYACWEGF
KTSGLTTRHC TTNGTWTGQP PDCTVISCGD PGPIANGIYL GREFTFNHTV AYRCNPGHLM
EPAGRNVLSC TKDGTWNQTK PSCKVIQCGH PPQVLNGKVE GTDHSWGSSV SYSCLQGYQM
SIPAVLTCEG NGTWTGDIPQ CLPVLCGDPG SPGEGFREGN IFSYGSEVRF YCHSPYVLVG
SATRLCQADG IWSGHQPTCI VCVDPAFNSC RDPGTPAYGI PIMAQGFQVG SKISFKCRKN
YHILGSTTRT CLENLTWSGT QPECIAHSCR QPETPSNVDV RAMDLPTLGY TLIYTCQEGF
YLSGGSEHRT CRSDGRWTGK PPLCKVGVKV NPKGRGESDI QKNKIRVPAD VFSPNSEWSG
FYEYLGKRQT TTFAVTGFNA TSSRVNVTLL ETSGVSIRLS GTYKSEENQL LLKVYQVKGP
TEYYYSKFKN DNWAMDGYVT AESDQKTFVY QGHIHSKDFG KFSLTRQGPV TTAMNPSNPY
TNSSSVVAAI LVPFFALILS GFAFYLYKHR TRPKVQFNGY VGHESSNGQA SFENPMYDTN
MKPTEAKAVR FDTTLNTVCT VV
//
