ID A0A087YFV5_POEFO Unreviewed; 1439 AA.
AC A0A087YFV5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Mannose receptor C-type 1 {ECO:0000313|Ensembl:ENSPFOP00000016908.2};
GN Name=MRC1 {ECO:0000313|Ensembl:ENSPFOP00000016908.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000016908.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000016908.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01006252; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007555723.1; XM_007555661.2.
DR STRING; 48698.ENSPFOP00000016908; -.
DR Ensembl; ENSPFOT00000016930.2; ENSPFOP00000016908.2; ENSPFOG00000016777.2.
DR GeneID; 103140480; -.
DR KEGG; pfor:103140480; -.
DR CTD; 100286774; -.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT01050000244842; -.
DR OMA; WIDKWRV; -.
DR OrthoDB; 4271106at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 8.
DR CDD; cd00062; FN2; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 8.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803:SF104; MACROPHAGE MANNOSE RECEPTOR 1; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 8.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR PRINTS; PR00013; FNTYPEII.
DR SMART; SM00034; CLECT; 8.
DR SMART; SM00059; FN2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 8.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 3.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 8.
DR PROSITE; PS00023; FN2_1; 1.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00479}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1439
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001834447"
FT TRANSMEM 1372..1394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 166..214
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 230..341
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 366..483
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 509..624
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 653..770
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 798..917
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 944..1070
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1092..1202
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1231..1345
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DISULFID 171..197
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 185..212
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
SQ SEQUENCE 1439 AA; 163801 MW; D762024C33619F23 CRC64;
MSPLSTFALI LCLLQALHIK ADIDSGIFLI FNQNHNKCIK VESASSVILA QCNPRASEQQ
FRWVSESRLL SLSLKLCLGA TAIKDWVKVL LFECDESSSL QHWQCKNETL FGLKDQDLHL
NWGNFKEKNV MIYKGAGEWS RWKIFGTQGD LCSKGFQETF TIRGNAFGAP CQFPFKYTSK
WYAECTTDGR TDGQLWCATE KDYHTNTKFG FCPTKGSIGW DTDPVTRVQY QRNTQATLTW
HQARVSCQQQ GADLLSIVEL HEQSYISGLT NHLGTSLWIG LNSLDFESGW QWSNGNPFRY
LNWAPGNPSS VPGESCAILN TRKASKWESS ICSKKLGYIC RKGNSTSLPP PPDKGPSFCP
SHWVPYGGQC YYLERSKKMW RDALAACHKE EADLASISNI EEQSFIITQS GYLQTDVLWI
GLNDQRNPML FEWSDRSHVT FTNWQSDEPS HATNHQEDCV LIRGKEGKWA DHMCEKTYGY
ICKKKASTKP TGGTQEEVNP GCKLGTTRFG SYCYEIGRET KSFEEAMQAC SKGGSNLVDI
ADRYENAFLI SLVGLRPERY FWTGLTNTEE INVFKWTTRR QVTFTHFNVG MPDRKQGCVA
MTTGTFAGLW DVISCSNKEK YICKKKAEGV LATTVQPTTP QLSCASGWTP VAKRNVCYKV
YKKMKENKKT WQEAQDFCKA IGGNLISLLS MRDLDNVNFY SSDPVWIGLR VMGPNQGFVW
SDGSPFSFEN WGFGEPNNHN DNEHCAEVHF HYSRHWNDRN CDSYNDWICQ IRKGVTPKPE
PVFVVEVFNT TEDGWLIYND SHYYINKNKL PMEAARDYCK KNFGELAVIT GESERKFLWK
HLTRDPQAQN HAQYYIGLIV NLDQSFSWVD GTPVTYTAWE NNEPNFANND ENCVTMYSSM
GYWNDINCGL ELPSICKRRG SFINTTMAPT TPPKGGCAPE WLNFKGKCYK FFADKKNWKD
ARTHCQKEGG NLVSITSERE QAFLTTQMLS QKEDLWLGMN DINWEMHFVW TDGKAISFTN
WAKGHPISTP DGRFFLDEVF DCVIMVGSIL KIKGQWKVED CSEKRGFVCK KNVDSQIAVP
ATTVSPKSFY KIGNDSYKVV AQKMRWDEAR RQCQADDSEL ASILNPMIQA FVTLQISTLK
EPVWIGLNNN VTGGRFKWVD NWLLSYTKWG KNEPKNYGCV YIDVDHTWKT AECSSTYYSI
CKRSQDLAPT EPPQLPGNCP EPKKDRSWMP FRGHCYYFVG SVVDNWAHAS VECMKLGASL
VSIQDPVEAK FIQKNIESLQ DETKSFWIGL YKSHDDEWMW IDNSVVDYTN WIIGMPKSDS
CVNIHSDSGK WSTNSCSRYR SYICKRPKVI PPTSKPQFVV QTVKEASLHG SAGITVAIVL
IVIAIVGLAA FLLFRKRIRL PMATLAECTF DNKLYFNNPN RVPVDTKGLV VNIEQNEQA
//
