ID A0A087YG49_POEFO Unreviewed; 1013 AA.
AC A0A087YG49;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Transmembrane protein 132D {ECO:0000313|Ensembl:ENSPFOP00000017002.2};
GN Name=TMEM132D {ECO:0000313|Ensembl:ENSPFOP00000017002.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000017002.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000017002.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the TMEM132 family.
CC {ECO:0000256|ARBA:ARBA00006166}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYCK01011771; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01011772; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087YG49; -.
DR STRING; 48698.ENSPFOP00000017002; -.
DR Ensembl; ENSPFOT00000017024.2; ENSPFOP00000017002.2; ENSPFOG00000016858.2.
DR eggNOG; KOG4789; Eukaryota.
DR GeneTree; ENSGT00940000158942; -.
DR OMA; VRGSCAM; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR026307; TMEM132.
DR InterPro; IPR031436; TMEM132_C.
DR InterPro; IPR031437; TMEM132_M.
DR InterPro; IPR031435; TMEM132_N.
DR PANTHER; PTHR13388:SF23; TRANSMEMBRANE PROTEIN 132C; 1.
DR PANTHER; PTHR13388; UNCHARACTERIZED; 1.
DR Pfam; PF16070; TMEM132; 1.
DR Pfam; PF15706; TMEM132D_C; 1.
DR Pfam; PF15705; TMEM132D_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 879..904
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..134
FT /note="Transmembrane protein TMEM132 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15705"
FT DOMAIN 390..726
FT /note="Transmembrane protein family 132 middle"
FT /evidence="ECO:0000259|Pfam:PF16070"
FT DOMAIN 848..932
FT /note="Transmembrane protein TMEM132 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF15706"
FT REGION 744..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..789
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1013 AA; 111476 MW; AD20E4B7B030B8DC CRC64;
PVFLPVNYEV RDADYLFLKE AGQDFMRNSS MQSHTQPFVL LRASRQPAVN ASYGPVSTER
LVPLDLVQSV QLFNAPDVFT FNWKIQAFVL TPRVFSSKPK VRVLFYVAGR DWARSEGASD
ELPCVTVYAF WQTQEVRGSC AIGGERGTCM AELLPEPGWF AAGSEGTGRE RQDPSAGNSV
ELYYQARPRV NGKCFSVNGS RWSSSAPPAE HVPVTPMQRI GSVQFLQIPK GMATLSRLKL
GNAIVIRTSS KPLKKTDIAT FYILMASSAQ LTNFTLRASV KKGVTFRTAT PSNSLLWDIT
LDMGADGAIA VICQRKAPIP GKRLESSLLE VLQMDFEVEE LSSPVDSQVI VWKLELPSAS
KTVAKTEGAM RIYTTQRDFV GLAPLVMDTE ILNTAVLTGK KVVMPVRTVA VEEDGLVTDV
SDYTDCGSSD EDVLKVSDRC DYVFVNGKEM KGKVKMVVNF TYSYLSAQLE LNVWMPQLPL
QIELSDTELS QIKSWRVPIL TSKRSGWNSE EAERKGKGCM LQLQHALVRV LTHFVAEQED
PRDPTAYFLG SDWQVDITRL VRYFMKVEDP RVARLQEGRV LSGRDFGTTN IQVFSPLSDV
VLAKTTVKVV DDKVSITELG VQVVSGLSMT LQRSSGSSRA ILATTTTQEV LQSPKQEALV
SSWVQFSDGN QTPLDIYDPA NYRLTVTSLD QGVVSVQGRP PLVVAEGEGE GVLVRVEMSI
CESCQKSKRK STVAVGNGSL KVKFQANTRR PGGATRSVDR SSVGNKDGNN DYGNDGEETD
VERKQRRPSQ FRPSSIPNSN KEESAIQKIP TTIRSTVKTM TSGSLGGVDK TFTSTVKAPG
NLVNYNDFPT KVEIPRPKMP EVESGEEALA NRPLTDLEIG MYALLGVFCL AILVFLVNCI
SYVVKFRHKK PPSHGQEPTG HRHDWVWLGT DAELVMTVPC SPVQQDSHTA TTVIDIGPDK
TASLSRRPSC LASATDSPLS CASSHRTNPI QSESLHSPTS KRKRVQFTTF STL
//
