ID   A0A087YH66_POEFO        Unreviewed;       302 AA.
AC   A0A087YH66;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=GDT1 family protein {ECO:0000256|RuleBase:RU365102};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000017369.2, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000017369.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
CC   -!- SIMILARITY: Belongs to the GDT1 family. {ECO:0000256|ARBA:ARBA00009190,
CC       ECO:0000256|RuleBase:RU365102}.
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DR   EMBL; AYCK01004058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_007550739.1; XM_007550677.2.
DR   AlphaFoldDB; A0A087YH66; -.
DR   STRING; 48698.ENSPFOP00000017369; -.
DR   Ensembl; ENSPFOT00000017391.2; ENSPFOP00000017369.2; ENSPFOG00000017287.2.
DR   GeneID; 103137112; -.
DR   KEGG; pfor:103137112; -.
DR   CTD; 55858; -.
DR   eggNOG; KOG2881; Eukaryota.
DR   GeneTree; ENSGT00390000005261; -.
DR   OMA; KSQLVCM; -.
DR   OrthoDB; 180756at2759; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IEA:Ensembl.
DR   Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR   InterPro; IPR001727; GDT1-like.
DR   InterPro; IPR049555; GDT1-like_CS.
DR   InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR   PANTHER; PTHR12608:SF1; TRANSMEMBRANE PROTEIN 165; 1.
DR   PANTHER; PTHR12608; TRANSMEMBRANE PROTEIN HTP-1 RELATED; 1.
DR   Pfam; PF01169; UPF0016; 2.
DR   PROSITE; PS01214; UPF0016; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365102};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Signal {ECO:0000256|RuleBase:RU365102};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU365102};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU365102}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   CHAIN           33..302
FT                   /note="GDT1 family protein"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT                   /id="PRO_5001834529"
FT   TRANSMEM        105..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        135..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        207..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
FT   TRANSMEM        277..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365102"
SQ   SEQUENCE   302 AA;  32424 MW;  31B35F455837DFC5 CRC64;
     MPVMLGRGDG GANRSLLFPL AAVLLLSVGV AAIQEEQKAV QEEPQKEKAT SPHPVGPIVT
     ENGSIKGNLG FIHAFVASFS VIIVSELGDK TFFIAAIMAM RYNRLTVLAG AMLALGFMTC
     LSVLFGYATT IIPRIYTYYV STALFAIFGV RMLREGLKMS PDEGQEELEE VQAEIKKKDE
     ELQRSKLANG APDVEAGTGT TLPQSKWHRF ISPIFIQAFT LTFLAEWGDR SQLATIILAA
     REDPFGVAVG GTIGHCLCTG LAVLGGRMIA QKISVRTVTI IGGIVFLAFA LSALFIKPES
     GL
//