ID A0A087YHY4_POEFO Unreviewed; 1314 AA.
AC A0A087YHY4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Nuclear factor of activated T cells 5a {ECO:0000313|Ensembl:ENSPFOP00000017637.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000017637.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000017637.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01001909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 48698.ENSPFOP00000017637; -.
DR Ensembl; ENSPFOT00000017659.2; ENSPFOP00000017637.2; ENSPFOG00000017540.2.
DR eggNOG; ENOG502QSVE; Eukaryota.
DR GeneTree; ENSGT00940000155213; -.
DR OMA; LPMGQQS; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd07882; RHD-n_TonEBP; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR015646; NFAT5_RHD_DNA-bd.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF10; NUCLEAR FACTOR OF ACTIVATED T-CELLS 5; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR01789; NUCFACTORATC.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 210..379
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 1..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 994..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1140..1159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1216..1238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 801..919
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 960..978
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1314 AA; 142363 MW; BE7126A5DA947FC2 CRC64;
MGLSTSSSDH LTVSQHLHST GADGPGASEM QGMEAAGSAP SRGGGGGGAS ATGGDGGTGV
LSGLGVQQLQ NTPSKRRPVL SISPPPEDLF DDSQMSCQEE PAVAAAACPD SEHSSSMWAD
DSVSNFSIIS SASYNDNTEV PRKSRKRTPR QRPGPKPTPP EDSMDVFDAD SAKGPHFVLS
QLSTDKTSSI ASSLDSGTAV KGGSLSAQFP QRSDGKELKI LVQPETQHRA RYLTEGSRGS
VKDRTQQGFP TVKLEGISEP VVLQVFVAND AGRVKPHGFY QACRVTGRNT TACKEVDIDG
TTVIEIPLEP SNDMTLAVDC VGILKLRNAD VEARIGVAGS KKKSTRARLA FRVNIPQPDG
SVLTLQVPSS PILCTQPAGL PEILKKSLHS GSVKGGEEVF IIGKNFLKGT KVIFQENIAD
DNSWQAEAKI DTDLFHQNHL VVTVPPFHSQ SITSPVSVGI FVMTNAGRSH EAQAFTYTPE
SADSSSGQTV KTEGASLVNT CIFDGQIKSV SSEQSDCSGQ PSKRQEDTPM EVSSNPQPTD
VFKPSPDPLI SVQQTLELNS SPHPGGEAFE SPMPLQPEDV ELPQAPPVFP SLESLGTIQK
QEISSTTSFP VSGDTTIPPV TPEVPQQFLR DPQESLSPES SDNGGTILVV AMPQMAAPAQ
PPPQQTQVDP FPHEGVAQLE RAVRELQAGG TTTLEQVLEV AVAQQQLNSV LYSPAPSAES
LQQHVQENMN SLRLGNSDGS LSARQQIQMQ QQQQQQQIQM QQQQQQQQIQ MQQQQQQQQI
QMQQQQQQQQ IQMQQQQQQQ QIQMQQQYQQ QQQILENLQQ QQQQQQQLQQ QVLSNMQIQQ
QLMLQPQDQQ QLQQQQQQQM MENIQQQLQQ NQQQQVLNNI QLQDQQQQQN QILSNLQQQQ
QEQQVLEKLQ QQLQAELLQP QIHSSPQAQQ PVSLLQQAGE LLTIQTSFPT PPPSHTSPPQ
QLFQSPQPLA ETQSSQQQVQ AALLQNTLTV LSGGGLGSEQ QPTGSTIFLS TNPQPQQSQQ
QPQLAFISSM ETSSSQPQPV SMFQNQPPTQ LSQPMEQQQS PQQNQQPPQQ LPLGQQGTLF
QRIPNHSQAN AVPQNQIAQP QQTGLLLCTS DLLFTTPAQA APPIASISVG IPQPDAAEPM
SFQVQSSSGS SAAPAANQQQ SLFQEQQPMQ GGVGVVANPG QQPPEQLFQT AVGGTVAPQG
QPNLFVFGIQ NDSSQLLSSS GPNLPAQTQA QNSGHMQPLL DQPMPQAAPG MHSNLQNTLQ
AQMQTSLENA LQSNTQTPMQ TQIQSSLQNQ MQATISATSG MDKIEDILES LQKQ
//
