ID A0A087YIA5_POEFO Unreviewed; 905 AA.
AC A0A087YIA5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Transmembrane protein 245 {ECO:0000313|Ensembl:ENSPFOP00000017758.2};
GN Name=TMEM245 {ECO:0000313|Ensembl:ENSPFOP00000017758.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000017758.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000017758.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
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DR EMBL; AYCK01006483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016528951.1; XM_016673465.1.
DR AlphaFoldDB; A0A087YIA5; -.
DR STRING; 48698.ENSPFOP00000017758; -.
DR Ensembl; ENSPFOT00000017780.2; ENSPFOP00000017758.2; ENSPFOG00000017604.2.
DR GeneID; 103140875; -.
DR CTD; 23731; -.
DR eggNOG; KOG2365; Eukaryota.
DR GeneTree; ENSGT00390000001667; -.
DR OMA; CVHFFWK; -.
DR OrthoDB; 3080970at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF4; TRANSMEMBRANE PROTEIN 245; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 646..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 741..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..792
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 799..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 838..863
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 33..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 885..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 905 AA; 100399 MW; A6A796BB5E66564F CRC64;
MFHFPTFPMF PWNSRYFYVI CFPPSRGRAV GRTTRSSSAV MADEEESAPE PAAVSPPGSP
HTGRPLSVSF SESVQPAVGM MSQLLSQPSS LKFDKNIKQA FYNTGAMIFV AICCGAAVLV
YFILEAFLRP LLWAVLCGTF LHPFKHSLAR LGRSWLSGLQ DTGTPIVVGT LLVPVWCVNY
GVEEMGKLVL KRLTVLLVIG AGAPLAYFLY LFWSVIGMQV ILGHVCWVIG VLLDCFHVVW
VCSVVFGYLL AVCLKWSPQT ECYLRAMALP VWAVLLFYIV SLTGSWRVPI FMVVVALLIV
GSLEKPPVPG KGELPGQMLS LAANTIFMAI SCSNLQPKAE SSEASSTGPV PPTPGFPRPL
KSSLQLKEKS SRKSSDIYFI LLVWAIVLVQ MWLNFWILQL LPIPVAVWVL KKLMVRFGVK
SFAERTLNSW WTVLEKFVWE REEALLPGPI KGLAQFLLRV DTKLWHWLNK QMIVWLERSL
DKIISIFIIF LLVTGTLLMA LLLTAMVHHE SAHIVEVASN LINETLSNHP EWANLLPEAR
VVQKALNSAA TNVYQHGREW ITQKLQKMLG DKVNNTAMIE KQVLELWDRL YHSWFVKNVT
HSGRHRVQKN MAHRQNSWLG DILDWKDIAS FVQENIETLL SILESLWVVM SRNVGLLFST
TTTLFTVLFH SGTALLNFAL SLVIFLTTLF YLLSSSGEYY KPVKWVINLT PLSQPGPSSN
IIGQSVEEAI RGVFDASFKM AGFYGLYTWL THTIFGINIV FIPSALAAIL GAVPFLGTYW
AAVPAVCDLW LAQGEGVKAA LLLICHLLPT YFVDTAIYSD ISGGGHPYLT GLAVAGGAYY
LGLEGAIIGP ILLCILVVAA NIYSAMLMSP SSALPTPVQP NWPTHPMRTF AESTPSVLKT
TSDSK
//
