ID A0A087YKL5_POEFO Unreviewed; 1939 AA.
AC A0A087YKL5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Myosin heavy chain, fast skeletal muscle-like {ECO:0000313|Ensembl:ENSPFOP00000018568.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000018568.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000018568.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; AYCK01000446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPFOT00000018590.2; ENSPFOP00000018568.1; ENSPFOG00000018505.2.
DR GeneTree; ENSGT00940000162888; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 4.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF44; MYOSIN-13; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 33..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..782
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 659..681
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1911..1939
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 846..1280
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 179..186
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1939 AA; 222248 MW; 8D6925C44D9C6721 CRC64;
MSGDSEMECF GPAAVYLRKP ERERIEAQNT PFDAKTAYFV TEPTEMYLKG KLVKKEGGKA
TVEVKGGKSI TVKEDEIFPM NPPKFDKIED MAMMTHLSEP SVLYNLKERY AAWMIYTYSG
LFCVTVNPYK WLPVYDAMVV AAYRGKKRIE APPHIFSISD NAYQFMLQDR ENQSILITGE
SGAGKTVNTK RVIQYFATIA VAGGKKSEPI PGKMQGSLED QIIAANPLLE AYGNAKTVRN
DNSSRFGKFI RIHFGTTGKL ASADIETYLL EKSRVTFQLS AERSYHIFYQ LATGHKPELI
AEGLLITTNP YDFPMISQGE ITVKSINDVE EFIATDTAID ILGFTAEEKA NIYKLTGAVM
HHGNMKFKQK QREEQAEPDG TEVADKIAYL MGLNSADMLK ALCYPRVKVG NEMVVKGQTV
PQVNNAVSAL CKSVYEKMFL WMVVRINEML DTKQPRSYFI GVLDIAGFEI FDFNSLEQLC
INFTNEKLQQ FFNHHMFVLE QEEYKKEGIE WEFIDFGMDL AACIELIEKP LGIFSMLEEE
CIVPKATDMT FKSKLYDQHL GKSAPFQKPK PAKGKAEAHF SLVHYAGTVD YNVVGWLDKN
KDPLNDSVVQ LYQKSSSKLL AHLYASHAGA DDAKGGKKGG GKKKGGSFQT VSALFRENLG
KLMTNLRSTH PHFVRCLIPN ESKTPGLMEN FLVIHQLRCN GVLEGIRICR KGFPSRILYG
DFKQRYKVLN ASVIPEGQFI DNKKASEKLL GSINIDHTQY RFGHTKVFFK AGLLGTLEEM
RDEKLAELVT MTQALCRGYV MRREFVKMME RREAIFTIQY NIRSFMNVKT WPWMKLYFKI
KPLLKSAETE KEMAQMKEDF AKTKEDLTKA LAKKKELEEK MVSLLQEKND LQLQIQSEGE
TLADAEERCE GLIKAKIQLE AKLKETNERL EDEEEINAEL TAKKRKLEDE CSELKKDIDD
LELTLAKVEK EKHATENKVK NLTEEMASQD ETIAKLTKEK KALQEAHQQT LDDLQAEEDK
VNTLTKAKTK LEQQVDDLEG SLEQEKKLRM DLERAKRKLE GDLKLAQETT MDLENDKQQS
EEKIKKRDFE ISQLLSKIED EQTIGSQLQK KIKELQARIE ELEEEIEAER AARAKVEKQR
ADLSRELEEI SERLEEAGGA TAVQIEMNKK REAEFQKLRR DLEEATLQHE ATAASLRKKQ
ADSVAELGEQ IDNLQRVKQK LEKEKSEYKM EIDDLSSNME STAKAKVNME KMCRSLEDQL
SELKTKNDEH IRQLNEINSH KARLVSENGE ISRQLEEKES LVSQLTRGKQ AFMHQIEELK
RHLEEEVKAK NALAHAVQSS RHDCDLLREQ YEEEQEAKAE LQRAMSKANS EVAQWRTKYE
TDAIQRTEEL EEAKKKLAQR LQDAEESIEA VNAKCASLEK TKQRLQGEVE DLMIDVERAN
ALAANLDKKQ RNFDKVLAEW KQKYEESQAE LEGAQKEARS LSTEMFKMKN SYEEALDHLE
TLKRENKNLQ QEISDLTEHI SETGKTIHEL EKGKKTAENE KVEIQTALEE AEATLEHEES
KILRVQLELT QVKSEIDRKL AEKDEEIEQI KRNSQRVMES MQSTLDAEVR SRNDALRIKK
KMEGDLNEME IQLSHANRQA AEAQKQLRNV QGQLKDAQLH LDEAVRAQDD MKEQVAMVER
RNTLMVAEIE ELRAALEQTE RSRKVAEQEL VDASERVTLL HSQNTSLINT KKKLEADFVQ
VQGEVEDAIQ EARNAEEKAK KAITDAAMMA EELKKEQDTS AHLERMKKNL EVTVKDLQHR
LEEAENLALK GGKKQLQKLE ARVRELEGEV EAEQRRGAEA IKGVRKYERR VKELTYQTEE
DKKNIARLQD LVDKLQLKVK SYKRQSEDAE EQANAHLSRY RKVQHELEEA QERADIAESQ
VNKLRAKSRE MGRGKEAEE
//
