ID A0A087YKX1_POEFO Unreviewed; 1377 AA.
AC A0A087YKX1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Roundabout guidance receptor 3 {ECO:0000313|Ensembl:ENSPFOP00000018674.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000018674.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000018674.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01006581; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006582; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006583; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006584; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01006585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 48698.ENSPFOP00000018674; -.
DR Ensembl; ENSPFOT00000018696.2; ENSPFOP00000018674.2; ENSPFOG00000018507.2.
DR eggNOG; KOG4222; Eukaryota.
DR GeneTree; ENSGT00940000155457; -.
DR OMA; NCCTTNH; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR GO; GO:0016199; P:axon midline choice point recognition; IEA:Ensembl.
DR GO; GO:0071679; P:commissural neuron axon guidance; IEA:Ensembl.
DR GO; GO:0048264; P:determination of ventral identity; IEA:Ensembl.
DR CDD; cd00063; FN3; 3.
DR CDD; cd07693; IgC_1_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF37; ROUNDABOUT GUIDANCE RECEPTOR 3; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 851..873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..108
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 114..201
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 206..290
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 295..388
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 399..485
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 506..601
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 620..712
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 717..818
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1013..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1232..1377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1128..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1159..1175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1232..1251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1289..1318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1339..1367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1377 AA; 149456 MW; BAFAF0DCB981486D CRC64;
SGSRPRLEDA APRIIEHPSD LIVSKGEPAT LNCKAEGRPT PTVEWYKDGE RVETDREDPR
SHRMLLPSGS LFFLRIVHGR RSKPDEGVYV CVARNYLGEA VSRNASLEVA ILRDDFRQTP
SDVVVAAGEP AVMECIPPRG HPEPTISWKR NNIRVNDRDE RITIRGGKLM ISNTRKSDAG
MYVCVGTNMV GEKDSDPAEL VVFERPVFTK QPVNQVVLAD DTVEFFCEVH GDPTPTVRWR
REEGELPRGR FEIRSDNSLR LSQVRAEDEG TYTCVSENSV GKAEASGTLQ VHVPPQIVVR
PRDQITAPGR TVTFLCGTKG NPPPAVFWQK EGSQILLFPI QEPSHSSRFS VSLSGELTIA
DVQVEDSGYY ICQAISVAGS ILTKALLEVE SAPSDRVPPI IRQGPGNHTL APGSTAQLHC
HVMGNPIPSI QWEKDGQRIL GNDGRVSLME NGTFQITRLQ ETDSGVYTCL ASSSSGETSW
SGVLTVKESA DRSVAQATEP FQLPGPPHKP IVTDVSKNSV SLTWQPNAHE GGAAVTSYII
EAFSQSAGST WQTVADMVKM ETHTITGLLP NTVYLFIVRA VNAYGLSDPS PISEPVRTQD
VSPTGQGVDH RQVQRELGEV AVQLQDPVML ATTSIRVSWT VDRQSPYVQG YRLFYRPSGG
TWLLQDINSP SERSTVLTGM LKGTEYEIKI RPYFDEFQGK DSRTLLIRTR EEVPSAPPRG
VTVATVKLSN SSSISVSWEP PPSDMQNGII QEYRVWCVGN GGDNQTRYYI NRTVDGTTQS
TVLKGLIPGV LYQVEVAAVT GAGVGTRSHP VSVLIKLPAE EPTAPGGGGG SAEEGSVSLA
EQITDVVKQP AFIAGIGGAC WVILMGFSLW IYCRRKKRKE LSHYTASFAY TPAVGFPHAE
ASGLTGRPGV LGGNMGNYPW LADSWPTTNL VHSSKEAVNC CTANHDPAER YYNEAGISNY
LNQTEKYSMG DSTEGPIYST IDATSEDLHS FTYGQNVSTT PYATASIMPF SSQPQGAAFS
GEQQDEGHWI TQPGPPQPAQ YAQPDRCAGK TRSKPKQKAM GKAVKTPSLT WMEALPPPPP
VGELGQCEQD GQLQHDNMDA RSDEEEWCPP LPDRTYLMEG CEDGPAPPQR NVTSSPATSY
SHQSTATLTP SPHEEARAPA DQQLARWEHP HTRSRRLPCG PVPVPQAPSP PLTQSNPSLC
GQQLLGSTEA GTLQFQSPAH CCLHGQAPTV NEDGATTPVH SRSSPAETCT PPNPKSRVKK
KASKTSAYRR DIQGDLPPPP EEDRLQGPQG CVETSSLANS ALSSLERSEY SSNSHQRKGS
GQKHADNEEV VVYSGKSGYL SRGQVSGNCS TTGSSSSRGS TGSRGLSSAR KHNEEMR
//
