ID A0A087YPY3_POEFO Unreviewed; 369 AA.
AC A0A087YPY3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Forkhead box protein E1 {ECO:0000313|Ensembl:ENSPFOP00000020086.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000020086.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000020086.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; AYCK01023137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007542308.1; XM_007542246.1.
DR AlphaFoldDB; A0A087YPY3; -.
DR STRING; 48698.ENSPFOP00000020086; -.
DR Ensembl; ENSPFOT00000020109.1; ENSPFOP00000020086.2; ENSPFOG00000019959.1.
DR GeneID; 103130754; -.
DR KEGG; pfor:103130754; -.
DR CTD; 2304; -.
DR eggNOG; KOG2294; Eukaryota.
DR GeneTree; ENSGT00940000165650; -.
DR OMA; HETPVFS; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20019; FH_FOXE; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF392; FORKHEAD BOX PROTEIN E1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 45..139
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 45..139
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 39942 MW; 5C78FCC11D5AE0A3 CRC64;
MTMPVVKVEK ESPADSGLPS SNPSPQTEDQ QPRGRRRKRP LQRGKPPYSY IALISMAIAN
SPDRKLTLGG IYKFITERFP FYRDNSKKWQ NSIRHNLTLN DCFIKIPREP GRPGKGNYWA
LDPNAEDMFE SGSFLRRRKR FKRCDLSTYA AYVHETPVFS PVQITRSAAY SGSVYPNMAV
NPAYGQQLPS AAYYPSSSPP GFAHSQTRMF SINNIIGHPA SAGMLAGQGA EMMQQPGRSF
SPEGLPNGSA ACSLGTPGFQ GQQCGGAVPP RSATHPGFTY SGPNGHPHHH AHQGSYGQGH
SPGYASAGRI HAAAHGSAET VDHYGRASPV QLGSFSQYNS AAAGAVTNSG SYLRHPSYPG
TMDRFVPAI
//
