ID A0A088F0J6_9SPHI Unreviewed; 1039 AA.
AC A0A088F0J6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Alpha-1,2-mannosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=KO02_09810 {ECO:0000313|EMBL:AIM36955.1};
OS Sphingobacterium sp. ML3W.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Sphingobacterium.
OX NCBI_TaxID=1538644 {ECO:0000313|EMBL:AIM36955.1, ECO:0000313|Proteomes:UP000028992};
RN [1] {ECO:0000313|EMBL:AIM36955.1, ECO:0000313|Proteomes:UP000028992}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ML3W {ECO:0000313|EMBL:AIM36955.1};
RX PubMed=25614576;
RA Smith S.A., Krasucki S.P., McDowell J.V., Balke V.L.;
RT "Complete Genome Sequence of Sphingobacterium sp. Strain ML3W, Isolated
RT from Wings of Myotis lucifugus Infected with White Nose Syndrome.";
RL Genome Announc. 3:0-0(2015).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR EMBL; CP009278; AIM36955.1; -; Genomic_DNA.
DR RefSeq; WP_038697815.1; NZ_CP009278.1.
DR AlphaFoldDB; A0A088F0J6; -.
DR STRING; 1538644.KO02_09810; -.
DR KEGG; sht:KO02_09810; -.
DR eggNOG; COG3537; Bacteria.
DR HOGENOM; CLU_003690_2_1_10; -.
DR OrthoDB; 9758101at2; -.
DR Proteomes; UP000028992; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR005887; GH92_a_mannosidase_put.
DR InterPro; IPR041371; GH92_N.
DR InterPro; IPR012939; Glyco_hydro_92.
DR InterPro; IPR029411; RG-lyase_III.
DR NCBIfam; TIGR01180; aman2_put; 1.
DR PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR Pfam; PF14683; CBM-like; 1.
DR Pfam; PF07971; Glyco_hydro_92; 1.
DR Pfam; PF17678; Glyco_hydro_92N; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000028992};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1039
FT /note="Alpha-1,2-mannosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001836937"
FT DOMAIN 29..186
FT /note="Rhamnogalacturonan lyase"
FT /evidence="ECO:0000259|Pfam:PF14683"
FT DOMAIN 309..548
FT /note="Glycosyl hydrolase family 92 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17678"
FT DOMAIN 554..1034
FT /note="Glycosyl hydrolase family 92"
FT /evidence="ECO:0000259|Pfam:PF07971"
SQ SEQUENCE 1039 AA; 118007 MW; 03B9C44B2718AB3F CRC64;
MNRHSRFLLT TGILFLVFGQ SALAQQSVIW QLGTADSSSA EFALSPGDYK NFLAHDMGYE
DKQVIIGQSQ LRKDVPYVLP GPANEWGGTG PTSGLRTHFL NFYYVLDQVN ATDSYNFEVD
LVNSDPKNHP TLQVSINGKN YNYAIENGAG TGQPGVGALG KKKLIVKPDP SLLRSGYNHI
TLTVLKGGWV EFDSFQLLGP EKTKLITDYN TLVKQIKVAD FESNSASGRV QNLLVEVLRL
KDDQNIKVLV DGKPIYQGNL NKGLSLLELP LAAVKERKKS ICEIYINDKL SARQQFIRAA
KRLGGASDYV NTMMGTAHSR WMIAPGPWMP FSMVKLSPDN QNVGWQAGYE PSMESIGAFS
HIHEWTMAGL GTFPTSGRLK TKVGDQYDPD SGYRSRIDKM TEHAPLGSYH VKLTDHDIDV
DLTQTTRASF QRYTFNKSDT GRVMIDLKVN GEYPYQIVDY KLKKVSDTKI IGYSSQLSEN
VWSTDAKQDY IVHFAIEFDR PIINFGTWEG DSISYIHDGE GTNVTDAGMF VEFDVRKQKT
VQLRTGVSYV SIENAEGNLR EEISQPFKWS FDQIVAHQHA VWNELLGRLE ITSDDYLEKE
KFYTNMYRAL ASRNTFSDSN GQWRDSREVV RVLGDKNDLA LGCDAFWNTF WNLNQFWNLV
TPEWSSKWVK SQLAMYDADG WLAKGPAGME YIPVMVAEHE IPLIVGAYQM GIRDYDVQKA
FAAVKKMQMT SPLKFEGGFA GNRDLDVYLK YKYVPSDLGR FSNSLEYSYD DWTVGQFAKS
LNKTADYEYF NDRGTWWKNA IDTSTGYARM KDSKGAWLKD FDPFKSGANH HYVEGNAWQL
TFFVPQDLPG LSKWIGEDVL LKRLEWGFGE SEKWRYNGPN DQYWDYPVVQ GNQQSMHFAY
IFNYMNKPWL TQKYSRSIAE RYYGQGISNA YLGDEDQGQM SAWYIMTAIG LFQMDGGTRS
NPVYEIGSPM FKEITIKLDN RYGRGKQFVI KAHNNSKQNM YVQAATLNGK RLDTFYFDAS
ELLKGGELVL EMGPEPNKQ
//
