ID A0A088T0Z4_9BACT Unreviewed; 250 AA.
AC A0A088T0Z4;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Uridine phosphorylase {ECO:0000256|ARBA:ARBA00021980};
DE EC=2.4.2.3 {ECO:0000256|ARBA:ARBA00011888};
GN Name=deoD_1 {ECO:0000313|EMBL:AIO18578.1};
GN ORFNames=KQ51_00698 {ECO:0000313|EMBL:AIO18578.1};
OS Candidatus Izimaplasma bacterium HR1.
OC Bacteria; Mycoplasmatota; Candidatus Izimaplasma.
OX NCBI_TaxID=1541959 {ECO:0000313|EMBL:AIO18578.1, ECO:0000313|Proteomes:UP000029408};
RN [1] {ECO:0000313|Proteomes:UP000029408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR1 {ECO:0000313|Proteomes:UP000029408};
RA Skennerton C.T., Haroon M.F., Tyson G.W., Orphan V.J.;
RT "Phylogenomic Analysis of Candidatus Izimaplasma species: Representatives
RT from a Novel Mollicute Clade found in Ocean Sediments.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AIO18578.1, ECO:0000313|Proteomes:UP000029408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR1 {ECO:0000313|EMBL:AIO18578.1,
RC ECO:0000313|Proteomes:UP000029408};
RX PubMed=27058507; DOI=10.1038/ismej.2016.55;
RA Skennerton C.T., Haroon M.F., Briegel A., Shi J., Jensen G.J., Tyson G.W.,
RA Orphan V.J.;
RT "Phylogenomic analysis of Candidatus 'Izimaplasma' species: free-living
RT representatives from a Tenericutes clade found in methane seeps.";
RL ISME J. 10:2679-2692(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=phosphate + uridine = alpha-D-ribose 1-phosphate + uracil;
CC Xref=Rhea:RHEA:24388, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001020};
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DR EMBL; CP009415; AIO18578.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A088T0Z4; -.
DR STRING; 1541959.KQ51_00698; -.
DR KEGG; mbj:KQ51_00698; -.
DR PATRIC; fig|1541959.3.peg.659; -.
DR eggNOG; COG2820; Bacteria.
DR HOGENOM; CLU_068457_1_0_14; -.
DR OrthoDB; 7945729at2; -.
DR Proteomes; UP000029408; Chromosome.
DR GO; GO:0004731; F:purine-nucleoside phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0004850; F:uridine phosphorylase activity; IEA:RHEA.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR CDD; cd09007; NP-I_spr0068; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR PANTHER; PTHR43691:SF11; FI09636P-RELATED; 1.
DR PANTHER; PTHR43691; URIDINE PHOSPHORYLASE; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:AIO18578.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029408};
KW Transferase {ECO:0000313|EMBL:AIO18578.1}.
FT DOMAIN 32..219
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
SQ SEQUENCE 250 AA; 28857 MW; 258AA854533BE9C9 CRC64;
MKAIPLLDFD SKRAMIEPSE QIKELPEMPK KVVLTFFKKE VDRLYEDCKT TKVHTLRSEM
GEHVVYKFMN EDVALFALGV GAPLAAGLFE ELIALGGRQF LCCCGAGVLI KKDLGCLVLP
NEGVRDEGTS FHYVEPSRTI KANKNTHEKV KNIMTEMRID YIVGKTWTTD AFYRETKQKV
NQRLYEGCLT VEMEFTALCA VAQYRNVEFA EILYCGDDLS REVWDGREWR EQELMRKDLI
FLTKNILERM
//
