ID   A0A088T2W0_9BACT        Unreviewed;       272 AA.
AC   A0A088T2W0;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|Pfam:PF01734};
GN   ORFNames=KQ51_01432 {ECO:0000313|EMBL:AIO19308.1};
OS   Candidatus Izimaplasma bacterium HR1.
OC   Bacteria; Mycoplasmatota; Candidatus Izimaplasma.
OX   NCBI_TaxID=1541959 {ECO:0000313|EMBL:AIO19308.1, ECO:0000313|Proteomes:UP000029408};
RN   [1] {ECO:0000313|Proteomes:UP000029408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HR1 {ECO:0000313|Proteomes:UP000029408};
RA   Skennerton C.T., Haroon M.F., Tyson G.W., Orphan V.J.;
RT   "Phylogenomic Analysis of Candidatus Izimaplasma species: Representatives
RT   from a Novel Mollicute Clade found in Ocean Sediments.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AIO19308.1, ECO:0000313|Proteomes:UP000029408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HR1 {ECO:0000313|EMBL:AIO19308.1,
RC   ECO:0000313|Proteomes:UP000029408};
RX   PubMed=27058507; DOI=10.1038/ismej.2016.55;
RA   Skennerton C.T., Haroon M.F., Briegel A., Shi J., Jensen G.J., Tyson G.W.,
RA   Orphan V.J.;
RT   "Phylogenomic analysis of Candidatus 'Izimaplasma' species: free-living
RT   representatives from a Tenericutes clade found in methane seeps.";
RL   ISME J. 10:2679-2692(2016).
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DR   EMBL; CP009415; AIO19308.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A088T2W0; -.
DR   STRING; 1541959.KQ51_01432; -.
DR   KEGG; mbj:KQ51_01432; -.
DR   eggNOG; COG1752; Bacteria.
DR   HOGENOM; CLU_034454_0_0_14; -.
DR   OrthoDB; 9770965at2; -.
DR   Proteomes; UP000029408; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd07209; Pat_hypo_Ecoli_Z1214_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF57; SLR0060 PROTEIN; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029408}.
FT   DOMAIN          7..200
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|Pfam:PF01734"
SQ   SEQUENCE   272 AA;  31389 MW;  8C4C3ADF0AFB6DBF CRC64;
     MKKLGIAFAG GGARGAYQIG AWQALKEHGL DTKFSAFSGA SVGSLNAVLF AMGDYDKAYE
     TWMSLDKKTL FNLEKHILKR LMKEKLNFIN RGVYNTRRLE KIIRNTIDFE SIRNKEIYIA
     TTHLGDQKST FFDLIRTNYK HFFKADQQIE YIDLNQFEDE DKLKTLLASC AIPVAFKPIE
     INKQTYYDGG LLDNTPYQPL IDAGCDVIIV IDLFTFSPMR IKKVQGVKLF TCYPKRSLRG
     ILDFNHKYIT RRFDLGYQDM SKLLEKIKDE LI
//