ID A0A089I3R7_9BACL Unreviewed; 584 AA.
AC A0A089I3R7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=H70357_20905 {ECO:0000313|EMBL:AIQ18881.1};
OS Paenibacillus sp. FSL H7-0357.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1536774 {ECO:0000313|EMBL:AIQ18881.1, ECO:0000313|Proteomes:UP000029508};
RN [1] {ECO:0000313|EMBL:AIQ18881.1, ECO:0000313|Proteomes:UP000029508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL H7-0357 {ECO:0000313|EMBL:AIQ18881.1,
RC ECO:0000313|Proteomes:UP000029508};
RA den Bakker H.C., Tsai Y.-C., Martin N., Korlach J., Wiedmann M.;
RT "Comparative genomics of the Paenibacillus odorifer group.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP009241; AIQ18881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A089I3R7; -.
DR STRING; 1536774.H70357_20905; -.
DR KEGG; paeh:H70357_20905; -.
DR eggNOG; COG2972; Bacteria.
DR HOGENOM; CLU_020473_6_0_9; -.
DR Proteomes; UP000029508; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..369
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 390..584
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 584 AA; 66744 MW; A74072FC6314FF88 CRC64;
MFVLIWGRRS KSIFVKFSAS FLLVGLIPLL ALSFFSVKTF SGYVERYTTS NLQQMVLYMS
YNLNTAFNQY NETSKLMYTG RYEGFIESYT QNQATNVNER EQINTIPIDS FLKTLLFSDP
YITGVQFVRQ SDGKIYSQEK ENRSLSGEPV PIPAWLAKME ENPSKVEIFP THIDNYFFQS
QRQVFTVGRS LIDTSGRVTK EPKVVGTLFL DIDTTLFQQF FRELNLGEKD ELYLLDGEGR
IYFSNQKETS GIIAQPDKQN NEMIILSEDI PFLQGKLIAK IHRGSLFEQL LSARTTVYIA
ILICAFVMII MGVWFSRRLA APIRELIKQM TVVESGKLDI QVSVNTNDEM GRLAHGFNRM
VERLQVYIDE AYVAQIKQKQ TELNALKSQI RPHYLYNTLE VIRMNAVDKE AGEVADMILA
LSNQLKYVID YGEDRVSLGS ELEHLQNYFY IISVRFENRY ELHLDIAADI QMDWPILKLS
LQPIVENAVQ HGLRLKGKGT VGITVERREN VLAVTVYDDG IGMNREELAR ITQSLNDAEA
PSKNVGLKNV HERIRSSFGE AYGLSVSSRE HIGTSITLLF PISE
//
