ID A0A089IAT6_9BACL Unreviewed; 380 AA.
AC A0A089IAT6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Homocysteine methyltransferase {ECO:0000313|EMBL:AIQ20200.1};
GN ORFNames=H70357_28480 {ECO:0000313|EMBL:AIQ20200.1};
OS Paenibacillus sp. FSL H7-0357.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1536774 {ECO:0000313|EMBL:AIQ20200.1, ECO:0000313|Proteomes:UP000029508};
RN [1] {ECO:0000313|EMBL:AIQ20200.1, ECO:0000313|Proteomes:UP000029508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL H7-0357 {ECO:0000313|EMBL:AIQ20200.1,
RC ECO:0000313|Proteomes:UP000029508};
RA den Bakker H.C., Tsai Y.-C., Martin N., Korlach J., Wiedmann M.;
RT "Comparative genomics of the Paenibacillus odorifer group.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-IPM synthase/homocitrate synthase
CC family. {ECO:0000256|RuleBase:RU003523}.
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DR EMBL; CP009241; AIQ20200.1; -; Genomic_DNA.
DR RefSeq; WP_038595922.1; NZ_CP009241.1.
DR AlphaFoldDB; A0A089IAT6; -.
DR STRING; 1536774.H70357_28480; -.
DR KEGG; paeh:H70357_28480; -.
DR eggNOG; COG0119; Bacteria.
DR HOGENOM; CLU_022158_4_2_9; -.
DR Proteomes; UP000029508; Chromosome.
DR GO; GO:0046912; F:acyltransferase activity, acyl groups converted into alkyl on transfer; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR Gene3D; 1.10.238.260; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR002034; AIPM/Hcit_synth_CS.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42880; HOMOCITRATE SYNTHASE; 1.
DR PANTHER; PTHR42880:SF1; ISOPROPYLMALATE_HOMOCITRATE_CITRAMALATE SYNTHASE FAMILY PROTEIN; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00815; AIPM_HOMOCIT_SYNTH_1; 1.
DR PROSITE; PS00816; AIPM_HOMOCIT_SYNTH_2; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AIQ20200.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003523}.
FT DOMAIN 4..257
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 380 AA; 41063 MW; CCDB9820C2EEA843 CRC64;
MKSLKLCDTT LRDGEQAAGV SFTRAEKLEI AKLLSECGVE QAEVGIPAMG KREQEDIAAI
AELGLPMKLM TWNRSVLGDI DKARSTGVNW SHVSIPVSEI QLQGKLGLTP AEGLNKLLRA
AEHGLRLGMT VSVGMEDSSR ANMEFLVELV NSLYKEGIRW FRYADTVSAH HPGQMAERVS
TLLGAVPADV ELEVHCHNDF GLACANTLSG IAAGAVWAST TVAGIGERTG NAAMEEVAMA
WRHLYGGESG VRMDLLKGLA DKVIAASGRS VGDAKPIVGQ LAFTHESGIH VDGLMKEKST
YQTFDPAEVG RTHRFVLGKH SGSNGVIHVL EQRGLEVNAD TAGRLLERVR VYAEARKGTV
PEYLLVQWLM EDQQRAQNAV
//
