ID A0A089LTH8_9BACL Unreviewed; 371 AA.
AC A0A089LTH8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Thiamine biosynthesis protein ThiH {ECO:0000313|EMBL:AIQ63385.1};
GN ORFNames=PSTEL_10085 {ECO:0000313|EMBL:AIQ63385.1};
OS Paenibacillus stellifer.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=169760 {ECO:0000313|EMBL:AIQ63385.1, ECO:0000313|Proteomes:UP000029507};
RN [1] {ECO:0000313|EMBL:AIQ63385.1, ECO:0000313|Proteomes:UP000029507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14472 {ECO:0000313|EMBL:AIQ63385.1,
RC ECO:0000313|Proteomes:UP000029507};
RA den Bakker H.C., Tsai Y.-C., Martin N., Korlach J., Wiedmann M.;
RT "Comparative genomics of the Paenibacillus odorifer group.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP009286; AIQ63385.1; -; Genomic_DNA.
DR RefSeq; WP_038694879.1; NZ_CP009286.1.
DR AlphaFoldDB; A0A089LTH8; -.
DR STRING; 169760.PSTEL_10085; -.
DR KEGG; pste:PSTEL_10085; -.
DR HOGENOM; CLU_046249_1_0_9; -.
DR OrthoDB; 9801120at2; -.
DR Proteomes; UP000029507; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR012726; ThiH.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR02351; thiH; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF1; 2-IMINOACETATE SYNTHASE; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00301; 2-iminoacetate_synthase_(ThiH); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000029507};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 68..291
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 371 AA; 41636 MW; 0E8ABD5CEDF60385 CRC64;
MSFYDTLLKL ESMPLGEQSG QYGRNDVERA LSREKLDPED LLALLSPAAV PYLEEMAQKA
HRITRAHFGY AVQLFTPMYV ADYCVNQCTY CSFSVEHDFA RKKLTMEEVD REASAIAATG
LRHILLLTGE SRKDSPVSYV KECAGVLRRH FSSVSIEVNP LSLEEYRELA ACGVDGLTMF
QEVYDRETYA RLHVKGPKRN FRARLDAPER GCQAGFRSVT IGALLGLSDW RREAFMTAMH
ARYLQDRYPG TEISIAPPRF RPYLGSFSPE SDVTDRALVQ IILAYRLFLP RSGLTLSTRE
PAALRDRLVH LGITKISAGV TTEVGGHTGG GGTPQFEISD ERSVPEIREM LYRSGLQPVF
KDWDILAEAP V
//
