ID A0A089WLR3_9PSED Unreviewed; 392 AA.
AC A0A089WLR3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AIR89536.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:AIR89536.1};
GN ORFNames=LK03_09680 {ECO:0000313|EMBL:AIR89536.1};
OS Pseudomonas cremoricolorata.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=157783 {ECO:0000313|EMBL:AIR89536.1, ECO:0000313|Proteomes:UP000029493};
RN [1] {ECO:0000313|EMBL:AIR89536.1, ECO:0000313|Proteomes:UP000029493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND07 {ECO:0000313|EMBL:AIR89536.1,
RC ECO:0000313|Proteomes:UP000029493};
RA Chan K.-G.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP009455; AIR89536.1; -; Genomic_DNA.
DR RefSeq; WP_038412114.1; NZ_CP009455.1.
DR AlphaFoldDB; A0A089WLR3; -.
DR STRING; 157783.LK03_09680; -.
DR KEGG; psw:LK03_09680; -.
DR eggNOG; COG0183; Bacteria.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000029493; Chromosome.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000029493};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AIR89536.1}.
FT DOMAIN 4..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 271..391
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 349
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 379
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 40465 MW; A57C204C8B1F8E6E CRC64;
MNEVAIVAAT RTAIGCFQGA LANVPAIELG AAVIRQLLTQ TGLDPAEVDE VILGQVLTAG
AGQNPARQSA IKAGLPHAVP ALTLNKVCGS GLKAVHLAAQ AIRCGDAEVV IAGGQENMSL
APYVLPSART GQRMGHGQML DSMISDGLWD AFNDYHMGIT AENLVDAYRL TRAEQDAFAA
ESQRKALAAI ASGRFVEEIT PVHIPQRKGP ARVFDTDEQP RAGTTAESLA GLRPAFRKDG
SVTAGNASTL NDGAAAVLLM SVSKAQALGL PVLATISGYA SAGVDPAIMG IGPVSATRRC
LEKAGWQLQD VELIEANEAF AAQALAVGRE LQWEASRVNV NGGAIALGHP IGASGCRVLV
TLLHEMLKRD AHKGLATLCI GGGQGVALAI SR
//
