ID A0A089XCF0_STRGA Unreviewed; 474 AA.
AC A0A089XCF0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Two-component system sensor kinase {ECO:0000313|EMBL:AIR99606.1};
GN ORFNames=SGLAU_18220 {ECO:0000313|EMBL:AIR99606.1};
OS Streptomyces glaucescens.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1907 {ECO:0000313|EMBL:AIR99606.1, ECO:0000313|Proteomes:UP000029482};
RN [1] {ECO:0000313|Proteomes:UP000029482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40922 / GLA O {ECO:0000313|Proteomes:UP000029482};
RX PubMed=25499805; DOI=10.1016/j.jbiotec.2014.11.036;
RA Ortseifen V., Winkler A., Albersmeier A., Wendler S., Puhler A.,
RA Kalinowski J., Ruckert C.;
RT "Complete genome sequence of the actinobacterium Streptomyces glaucescens
RT GLA.O (DSM 40922) consisting of a linear chromosome and one linear
RT plasmid.";
RL J. Biotechnol. 194:81-83(2015).
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DR EMBL; CP009438; AIR99606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A089XCF0; -.
DR STRING; 1907.SGLAU_18220; -.
DR KEGG; sgu:SGLAU_18220; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_1_11; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000029482; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AIR99606.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029482};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 48..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..295
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 352..442
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT REGION 447..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 50546 MW; 3A437BD41F1AE88A CRC64;
MPRVDHVTET GRDRHPEGSR PGDWLRVLRA DLWTFRADPL PPFLWLRWLP HGLVCLAGVI
VLGTSASLLD DTYGQNAQYA LLMSAGQGAA VVLALWRPVP AWLLSTAVSV AIALAARSQL
ISGQSAPDAA WPWAAPGVAA HSLVLLLLAL RVPTRVAFEA LAVTALATYL VQGVIGASRY
AGTGVVAVSV FTVVVLLGVA LRGRREARDE LGRQTTITAE ERARRTVLEE RSRIARELHD
VVAHHMSVIS IQAQVAPHLV DDPSDELKEN LAGIRQNALE ALTELRRVLG VLRSENPEDP
YGLGESGAGA APDAPQPTLD RLDALIENTR AAGLCVTADV RGEPRRPYPP GVELSAYRIV
QEALSNALRH APGSDVRVRV GHVPEGLLLE ITNSRPERAV PSSPGAGHGL LGMRERAAML
GGYVRARPAP HGGFGVVAFL PRDGVARDPL DEDVQGPPGA EYTVPEPPTG EGIP
//
