ID   A0A089Z4V2_STRGA        Unreviewed;       354 AA.
AC   A0A089Z4V2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Putative adenosine/adenine deaminase 1 {ECO:0000313|EMBL:AIS00816.1};
DE            EC=3.5.4.- {ECO:0000313|EMBL:AIS00816.1};
GN   ORFNames=SGLAU_24370 {ECO:0000313|EMBL:AIS00816.1};
OS   Streptomyces glaucescens.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1907 {ECO:0000313|EMBL:AIS00816.1, ECO:0000313|Proteomes:UP000029482};
RN   [1] {ECO:0000313|Proteomes:UP000029482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40922 / GLA O {ECO:0000313|Proteomes:UP000029482};
RX   PubMed=25499805; DOI=10.1016/j.jbiotec.2014.11.036;
RA   Ortseifen V., Winkler A., Albersmeier A., Wendler S., Puhler A.,
RA   Kalinowski J., Ruckert C.;
RT   "Complete genome sequence of the actinobacterium Streptomyces glaucescens
RT   GLA.O (DSM 40922) consisting of a linear chromosome and one linear
RT   plasmid.";
RL   J. Biotechnol. 194:81-83(2015).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; CP009438; AIS00816.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A089Z4V2; -.
DR   STRING; 1907.SGLAU_24370; -.
DR   KEGG; sgu:SGLAU_24370; -.
DR   eggNOG; COG1816; Bacteria.
DR   HOGENOM; CLU_039228_7_1_11; -.
DR   Proteomes; UP000029482; Chromosome.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   CDD; cd01320; ADA; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR   PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:AIS00816.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029482}.
FT   DOMAIN          19..342
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   354 AA;  38635 MW;  D7FBAB71D4C27AD7 CRC64;
     MTDRSVAQPT AGDFIAGLPK AELHVHHVGS ASPRIVAELA SRHPDSKVPT DPEALVDYFT
     FTDFAHFIEV YLSVVDLIRT PEDVRLLTYE VARELARQQV RYAELTITPF SSTRRGIDEK
     AFMEAIEDAR KAAEAEFGTV LRWCFDIPGE AGLEAAEETT RLATDDRVRP EGLVSFGLGG
     PEIGVPRPQF KPYFDRAIAA GLRSVPHAGE TTGPQTVWDA LTHLRAERIG HGTSSARDGK
     LLAHLAEHRI ALEVCPTSNI ATRAVRTLDE HPLREFVDAG VLVTVNSDDP PMFGTDLNTE
     YAVAARLLDL DERGLASLAK NAVEASFLDP AGKARLAAEI DTYTDAYLAD RLAP
//