ID A0A089Z761_STRGA Unreviewed; 805 AA.
AC A0A089Z761;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=beta-mannosidase {ECO:0000256|ARBA:ARBA00012754};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
GN ORFNames=SGLAU_28395 {ECO:0000313|EMBL:AIS01616.1};
OS Streptomyces glaucescens.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1907 {ECO:0000313|EMBL:AIS01616.1, ECO:0000313|Proteomes:UP000029482};
RN [1] {ECO:0000313|Proteomes:UP000029482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40922 / GLA O {ECO:0000313|Proteomes:UP000029482};
RX PubMed=25499805; DOI=10.1016/j.jbiotec.2014.11.036;
RA Ortseifen V., Winkler A., Albersmeier A., Wendler S., Puhler A.,
RA Kalinowski J., Ruckert C.;
RT "Complete genome sequence of the actinobacterium Streptomyces glaucescens
RT GLA.O (DSM 40922) consisting of a linear chromosome and one linear
RT plasmid.";
RL J. Biotechnol. 194:81-83(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CP009438; AIS01616.1; -; Genomic_DNA.
DR RefSeq; WP_043505319.1; NZ_CP009438.1.
DR AlphaFoldDB; A0A089Z761; -.
DR STRING; 1907.SGLAU_28395; -.
DR KEGG; sgu:SGLAU_28395; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_005015_3_2_11; -.
DR OrthoDB; 9758603at2; -.
DR Proteomes; UP000029482; Chromosome.
DR GO; GO:0004567; F:beta-mannosidase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000029482}.
FT DOMAIN 196..286
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
SQ SEQUENCE 805 AA; 89768 MW; 77880AA942FDA4EA CRC64;
MKEVVPLTEG WSLHHNGNPL PATVPGCVHT DLLAAGEIPD PYTGLNEREV QWVGRRAWTY
ARDLAPADTA ADSHERTDLV FDGLDTAATI TLDGRELGRT RNMHRRYRFD VTGRHGRLHV
EFASAYDEAG SVRALTGERP NVYPEPFQYI RKMACSFGWD WGPTLVTAGI WRPVRLERWS
TARLAEVRPL VTADDGTGRV ELHVAVERTG SGAGRPLTVH ASVGGVRQRV TVDGTRAVVT
LDVPDVDLWW PRGYGEQPLY DLEVTLVEDG PQERRLDSWH RRIGFRTVRL DRSADEHGTG
FTFVVNGVRI FARGVNWIPD DTFPSRITPE RYRTRLTQAA EANVDLVRVW GGGIYEDDAF
YDTCDELGLM VWQDFLFACA AYPEEQPLRG EVEAEARDNV VRLMPHPSLV LWNGNNENLW
GFRDWDWEPA LEGDSWGGGY YLDLLPRIVA ELDPTRPYTA GSPWSGSWDH HPNDPAHGTH
HSWEVWNRRD YAEYRDSVPR FVAEFGWQAP PAHATLRRAL PGEELAPDSP GMLHHQKAED
GNGKLNRGIA RHFELPEDDF DHWHYLAQVV QARAVAAGIE HWRAHWPVCA GTVVWQLNDC
WPVSSWAAVD GDGRRKPLHH ELRRVYADRL LTLRPGPGGP ALAVINQGAA LWRATVTLRR
LRADGTVAGH TTVEATAGAR EVARHAVPRD LVPDERSGKE FLVADADGLR AVHFPVPDKE
FAYPAPRYDV EVVPAGDGGS VEVVVTAHTL VRDLLLQPDR LGADAACDTG LHTLLPGEHV
RLRVRGAGAV TADAARAALF CVAQR
//
