ID A0A090CYX5_9BACT Unreviewed; 558 AA.
AC A0A090CYX5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative K(+)/H(+) antiporter {ECO:0000313|EMBL:CDR33811.1};
GN ORFNames=CSEC_0984 {ECO:0000313|EMBL:CDR33811.1};
OS Criblamydia sequanensis CRIB-18.
OC Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Criblamydiaceae;
OC Criblamydia.
OX NCBI_TaxID=1437425 {ECO:0000313|EMBL:CDR33811.1, ECO:0000313|Proteomes:UP000031552};
RN [1] {ECO:0000313|EMBL:CDR33811.1, ECO:0000313|Proteomes:UP000031552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIB-18 {ECO:0000313|EMBL:CDR33811.1,
RC ECO:0000313|Proteomes:UP000031552};
RA Linke B.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDR33811.1, ECO:0000313|Proteomes:UP000031552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIB-18 {ECO:0000313|EMBL:CDR33811.1,
RC ECO:0000313|Proteomes:UP000031552};
RA Bertelli C., Goesmann A., Greub G.;
RT "Criblamydia sequanensis harbors a mega-plasmid encoding arsenite
RT resistance.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDR33811.1}.
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DR EMBL; CCEJ010000004; CDR33811.1; -; Genomic_DNA.
DR RefSeq; WP_041017359.1; NZ_CCEJ010000004.1.
DR AlphaFoldDB; A0A090CYX5; -.
DR STRING; 1437425.CSEC_0984; -.
DR eggNOG; COG1226; Bacteria.
DR eggNOG; COG4651; Bacteria.
DR OrthoDB; 9793589at2; -.
DR Proteomes; UP000031552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR42751:SF1; CATION_PROTON ANTIPORTER YBAL-RELATED; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031552};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 422..542
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 558 AA; 60561 MW; C29B234312BE3339 CRC64;
MGEELKVIWL LAIGLGLACL CGYIAQRFKQ SPIIGYLIAG FLIGPNSPGF AADPYITEQL
ANIGVTLLMF VVGLNFNWKD LLEVKKIAIP GALILSAISI LVGILYTHFL GESLLAGLVI
GIAISVSSTV VIVRVLSDRG LFQTKQGHLI VGWTIVEDLI SVFGLLLLPA IVTASVGASD
SKLNVVYEIL LVLVKITALG FIIHLFGEKV VENILKVVAR ARSHELFTMA ILSTTFMIAI
VSSYSFGVSL ALGAFIAGVI VGKTDMSYQA AANALPLRDT FAAVFFLSVG MLFNPVTIMN
NLPLFLGILV IILVMRPIIA FLIVKIAKYP SSVAMAVGLA IAQIGEYSFI LAEEGNYLGI
LPDNAYDIII GCAFVTISLN PILFKLFNIT GARDKRYSNV PQELSIQHLS DDADNNRSFL
PRAIVIGFGP IGQAAVHEIL KRGYHVTVVD QNIDAIAALK NRKLEAIYGD ATQFHILEKA
QLENARLLVV ATPEFSATRS IIQVAQNTNP NLKIIARSRY KASLADQYFS DIPFICDEEA
TSEKLISYLR DELDKMGN
//
