ID   A0A090CZ26_9BACT        Unreviewed;       462 AA.
AC   A0A090CZ26;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Alanine/glycine:cation symporter {ECO:0000313|EMBL:CDR33946.1};
GN   Name=agcS {ECO:0000313|EMBL:CDR33946.1};
GN   ORFNames=CSEC_1120 {ECO:0000313|EMBL:CDR33946.1};
OS   Criblamydia sequanensis CRIB-18.
OC   Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Criblamydiaceae;
OC   Criblamydia.
OX   NCBI_TaxID=1437425 {ECO:0000313|EMBL:CDR33946.1, ECO:0000313|Proteomes:UP000031552};
RN   [1] {ECO:0000313|EMBL:CDR33946.1, ECO:0000313|Proteomes:UP000031552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIB-18 {ECO:0000313|EMBL:CDR33946.1,
RC   ECO:0000313|Proteomes:UP000031552};
RA   Linke B.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDR33946.1, ECO:0000313|Proteomes:UP000031552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIB-18 {ECO:0000313|EMBL:CDR33946.1,
RC   ECO:0000313|Proteomes:UP000031552};
RA   Bertelli C., Goesmann A., Greub G.;
RT   "Criblamydia sequanensis harbors a mega-plasmid encoding arsenite
RT   resistance.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDR33946.1}.
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DR   EMBL; CCEJ010000004; CDR33946.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A090CZ26; -.
DR   STRING; 1437425.CSEC_1120; -.
DR   eggNOG; COG1115; Bacteria.
DR   Proteomes; UP000031552; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031552};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        73..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        100..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        144..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        178..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        215..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        251..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        310..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        354..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        399..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        423..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   462 AA;  49182 MW;  51CB5264B69956B1 CRC64;
     MTEMSSWIAG FLDKVYAIVW SFPLLLLIVG IGIYLTFLLK GIQFRYLGYA FKLVVSNKQY
     KGEKGDISNF ESLMTALAAT IGIGNIAGIS TAVVTGGLGA LFWMWVTALI GMATRYAESI
     LAVKYRTTDS KGEMCGGPMY FIEYALGWKW LSISFAFFGA IAAFGGGNML QANSVADVMY
     GTFSVSPLYT GILVAAFTGL TILGGIKSIG KVASFLVPMM AFIYIGGALI ILGAKFYLIP
     GVLATIFKTA FTGQAAVGGF LGSTIILAFQ MGISRGLMTS EAGLGTASIA AAAAQTDVPG
     RQALVSMTGC FLATIVMCTV TGLVLGVTNV LGMTGEGGKA VTGASLTMAA FSSVFPWGGY
     IVTFGLILFA FTTLVGWAYY GEKCCEYLFG DKSVPFYRIL FTLIVIPGAV LELDLVWKIS
     DIFNGLMAFP NLIALLALSP VVKEETKHFI ELLKKEKKQE LS
//