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Database: UniProt
Entry: A0A090IQP6_9GAMM
LinkDB: A0A090IQP6_9GAMM
Original site: A0A090IQP6_9GAMM 
ID   A0A090IQP6_9GAMM        Unreviewed;       357 AA.
AC   A0A090IQP6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-MAY-2019, entry version 23.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroF {ECO:0000313|EMBL:CED70625.1};
GN   ORFNames=AWOD_I_0531 {ECO:0000313|EMBL:CED70625.1};
OS   Aliivibrio wodanis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Aliivibrio.
OX   NCBI_TaxID=80852 {ECO:0000313|EMBL:CED70625.1, ECO:0000313|Proteomes:UP000032427};
RN   [1] {ECO:0000313|EMBL:CED70625.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Hjerde Erik;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; LN554846; CED70625.1; -; Genomic_DNA.
DR   RefSeq; WP_045101319.1; NZ_LN554846.1.
DR   EnsemblBacteria; CED70625; CED70625; AWOD_I_0531.
DR   GeneID; 28540086; -.
DR   KEGG; awd:AWOD_I_0531; -.
DR   PATRIC; fig|80852.17.peg.539; -.
DR   KO; K01626; -.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000032427; Chromosome 1 complete sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032427};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:CED70625.1}.
FT   DOMAIN       41    340       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   357 AA;  39635 MW;  CB50EE0B11CE4579 CRC64;
     MKKSELSNIN ISDEQVLITP QELKNQIPLS DNARLFIQQS RQTISNIIHK KDHRLLIVCG
     PCSIHDIDAA KEYAKRLKVI SEDLKDQLYI VMRVYFEKPR TTVGWKGLIN DPHLDGSFDI
     DHGLHAARQL LVDLAEMEIP LATEALDPIS PQYIGDTFSW AAIGARTTES QTHREMASGL
     SVPVGFKNGT DGSLSTSINA MQAAASSHRF MGINNEGQVA LLTTQGNPNG HVILRGGKQT
     NYDSVSVTEC EEELAKSNLE AALMIDCSHA NSRKDYRRQP LVAEDVIHQI REGNKSIIGL
     MIESHLNEGN QPSDIPLSEM KYGVSITDAC INWDSTEALL RHTHKELIPV LEERLKG
//
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