ID A0A090L244_STRRB Unreviewed; 206 AA.
AC A0A090L244;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=PMP-22/EMP/MP20/Claudin superfamily-containing protein {ECO:0000313|EMBL:CEF63742.1, ECO:0000313|WBParaSite:SRAE_1000200000.1};
GN ORFNames=SRAE_1000200000 {ECO:0000313|EMBL:CEF63742.1,
GN ECO:0000313|WBParaSite:SRAE_1000200000.1,
GN ECO:0000313|WormBase:SRAE_1000200000};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF63742.1};
RN [1] {ECO:0000313|EMBL:CEF63742.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_1000200000.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF63742.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_1000200000.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM47 family.
CC {ECO:0000256|ARBA:ARBA00008691}.
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DR EMBL; LN609528; CEF63742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090L244; -.
DR STRING; 34506.A0A090L244; -.
DR EnsemblMetazoa; SRAE_1000200000.1; SRAE_1000200000.1; WBGene00258612.
DR WBParaSite; SRAE_1000200000.1; SRAE_1000200000.1; WBGene00258612.
DR WormBase; SRAE_1000200000; SRP00009; WBGene00258612; -.
DR OMA; FVETATM; -.
DR OrthoDB; 5399051at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0030054; C:cell junction; IEA:EnsemblMetazoa.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:EnsemblMetazoa.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:EnsemblMetazoa.
DR GO; GO:0045087; P:innate immune response; IEA:EnsemblMetazoa.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR015664; P53_induced.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR PANTHER; PTHR14399:SF5; CELL JUNCTION PROTEIN VAB-9; 1.
DR PANTHER; PTHR14399; P53-INDUCED PROTEIN RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 206 AA; 23028 MW; 0896A49B6878F9C8 CRC64;
MVAQTTTIES VTVIRPLKIT ALLCLIISLG LMIAALSTNN WLRTGSYHTG LFNECTDTGG
LDSLIKPISG SPLPGQCQKT KDYAYVKAVI SLLIISCIII LFASISNILG LKSDDQHRKY
LYHKVATGLT FLAVLCDILS LIIYPACFYN IMSMLQIRHW ELDYSYAIAW GAFSFAFTAL
LLKICDKEHE EVYYKEKTVY NPPQLS
//
