ID   A0A090L5M1_STRRB        Unreviewed;      1223 AA.
AC   A0A090L5M1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=SH3 domain and Variant SH3 domain-containing protein {ECO:0000313|EMBL:CEF62769.1, ECO:0000313|WBParaSite:SRAE_1000103800.1};
GN   ORFNames=SRAE_1000103800 {ECO:0000313|EMBL:CEF62769.1,
GN   ECO:0000313|WBParaSite:SRAE_1000103800.1,
GN   ECO:0000313|WormBase:SRAE_1000103800};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF62769.1};
RN   [1] {ECO:0000313|EMBL:CEF62769.1, ECO:0000313|Proteomes:UP000035682}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC   ECO:0000313|WBParaSite:SRAE_1000103800.1}, and ED321 Heterogonic
RC   {ECO:0000313|EMBL:CEF62769.1};
RA   Martin A.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_1000103800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (DEC-2020) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LN609528; CEF62769.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A090L5M1; -.
DR   STRING; 34506.A0A090L5M1; -.
DR   EnsemblMetazoa; SRAE_1000103800.1; SRAE_1000103800.1; WBGene00257639.
DR   WBParaSite; SRAE_1000103800.1; SRAE_1000103800.1; WBGene00257639.
DR   WormBase; SRAE_1000103800; SRP08158; WBGene00257639; -.
DR   eggNOG; KOG3544; Eukaryota.
DR   OMA; PIWDEPE; -.
DR   OrthoDB; 2884121at2759; -.
DR   Proteomes; UP000035682; Chromosome X.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   PANTHER; PTHR32083; CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED; 1.
DR   PANTHER; PTHR32083:SF0; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 58; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          154..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          531..552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          833..856
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1152..1223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          889..1046
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        155..169
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        833..848
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1223 AA;  136117 MW;  78935D4A1B2C28CF CRC64;
     MTRNLAFSKI LSSFLFIFFI ILLINYKTKV NCVISKEKTK TCKDVNCTGV FFSTKVIRNY
     KSTHPNFSNL KMGDTIDVVA IKFSHRGDIM EGIVNGERGY FYTNFVDKDP YHSFLINITA
     TDENILSVVS FSEDKIDFLD SDLHVAFNPN GVYVPKKSKE DDSGHGHSHG GHGHSHGGHG
     HSHEETSHNH GHIHEEKIIT TTVVPSVEKK IEANKDVPSM NTVTNDLTTT TPSPNVEDQK
     LTLQNDIIIS SSVPPPINVP NQDFNNNIIN ENPTFENINN KNEIFKDNVE NEKIVTNIND
     MHGNLDKIKS EIIQEAFASI TADTEPQILN SETVTPTPID AGVNLPSTDN SGATVPPPVV
     AASTTLAPTI SVVTTPAPTI SAVTTPAPTI SAVTTPAPTI SAVTTPAPTI SAVTTPAPTI
     SAVTTPAPTI STVTTPSPTI SEISKPIVEE VTTQSTVFVE NSMPSIPHEH VTPPVPNIDE
     IVSPPPIVVD TTTAAPMVNE QTVTPSSIES ISLPPLGDLL TVPSLRESPP LNKADIPIKG
     EGETVPSSMS VDSSANETFE TKENISQEGV IYDNNKTKEI EEEKSFLQLY IGYYLKLAVS
     SFRETLPEPL SKVDDSGIIL LILAPISIII HLTNKFLLSD DGSQEVFERK YLHDSLTKIK
     EQEVMINKLK ETQADPQLMK QFQGLKEEYE RIYRENQELL KVKESLSYEN NNFKKMFERK
     ENENITLKDE LKVIKDKLHS KDESITSLEM KSSKLQSDNN NLSKENNELK DILDEKNKKI
     IEYSKECEKN IEENKNLKHQ IIDIEEQLKN GKDEHDKLRK EIEGLSELLE EMNQNSQNQD
     NEGAGSIGST GWSDVGDVEI ESAGSNSLGC NKTVKRRSPD LSGGNLLDLA RSRAEIKRLE
     QEIENITVKL TKETVEKDSL LNRISLLEHE IDAQKNELTH NAVERNENSA QISRLLTLVE
     ERSNEIKDLQ SREKQLRNEY VELDQKYRDL RDEKLGVEFK CKESESLVKS LQSEVNKLET
     INYNEVRKLK NQLKLLEEEK NSEIKEFAGG NSSRQSIGLS EGLPITATNP LMNSSGPIRP
     LWSDVDDAPV ASSTMRNQAS LFGSELDSSD NGSLKKNVKI RKSMKKSKPP LHEGMLNMSY
     NNYGIPPPHL EYASSSGRRS VGREMLHGGS QTLHNGGTRR TRSRSQGREG ERLVSPLTFT
     GYDFPEYQQH SFHHPQPSNQ RQK
//