ID   A0A090LA73_STRRB        Unreviewed;      1096 AA.
AC   A0A090LA73;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=Protein-tyrosine phosphatase, receptor/non-receptor type domain and Protein-tyrosine/Dual specificity phosphatase domain and Protein-tyrosine phosphatase, catalytic domain-containing protein {ECO:0000313|EMBL:CEF64420.1};
GN   ORFNames=SRAE_1000267400 {ECO:0000313|EMBL:CEF64420.1,
GN   ECO:0000313|WBParaSite:SRAE_1000267400.1,
GN   ECO:0000313|WormBase:SRAE_1000267400};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF64420.1};
RN   [1] {ECO:0000313|EMBL:CEF64420.1, ECO:0000313|Proteomes:UP000035682}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC   ECO:0000313|WBParaSite:SRAE_1000267400.1}, and ED321 Heterogonic
RC   {ECO:0000313|EMBL:CEF64420.1};
RA   Martin A.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_1000267400.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (DEC-2020) to UniProtKB.
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DR   EMBL; LN609528; CEF64420.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A090LA73; -.
DR   STRING; 34506.A0A090LA73; -.
DR   EnsemblMetazoa; SRAE_1000267400.1; SRAE_1000267400.1; WBGene00259290.
DR   WBParaSite; SRAE_1000267400.1; SRAE_1000267400.1; WBGene00259290.
DR   WormBase; SRAE_1000267400; SRP04055; WBGene00259290; -.
DR   OrthoDB; 1342035at2759; -.
DR   Proteomes; UP000035682; Chromosome X.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd00047; PTPc; 1.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR46163:SF17; TYROSINE-PROTEIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46163; TYROSINE-PROTEIN PHOSPHATASE-RELATED; 1.
DR   Pfam; PF00102; Y_phosphatase; 2.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 2.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:CEF64420.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        427..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          527..746
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          803..1064
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          986..1055
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
SQ   SEQUENCE   1096 AA;  127883 MW;  82FD0116BB643783 CRC64;
     MNKTTFPVNI NSNSSSNVIL LKCPDNKYRH LTVNDTFTLD DSSDFRKLTI RTESKTFAWT
     LLGYNLFGPH LVHCGVFGKA FSDGNHTNFN WKFNFNWELA PNPYMVAKRI TINNQLLHPD
     ECGNDEKKVL KFTKDKTGKI FQLQLVRNKL KTRDELPYVN KLYYLFTIPE DTYEKEIVEP
     CLIYRAINDI PEIIVKGYNS TLIKPNGTDI DVIKFDYLEK FLEIQLLLTD QPNLKDFYKN
     EEILISKLLY TKDGVKEVPN SNKTTKGTFS LNGYELLKFS YDCPSIGRNR MITKILYFAP
     PQENFTYPLE YILYSSNETV VRPNCSINRF SFGYLYSVDY INKKIVNLTE LNVNGVAKDG
     LYRSGDFVFT SEVKNFNTTL KCLYKTPNGE VTLIHSFLRN DKPSSEKAES TNKNTQKSGF
     EKFKEKFGFF GAISIIVGSV IIGILIFIGF CALIFLKQIK LYIRKKKLAS KYPNVFALWK
     EVSNANLEKY CKIVQDENYI PDILMRQSFL KKIEGDEEVD YDTSTRFDSS LVKCFKSISE
     EIRAHYINDI SPERNYIISD GPTPEKIQYF WELLYKEDAT VVVAMIYHDN EDNPETNNKL
     LYWPEKNQTY GNVTVKFLEE LPTNLISVKI LKFNMTMKGE KSKELTIFHV KDWKEYTIPN
     TDLDFTKLHS EVSECAGNKN ILVHASRNAG SSVFIFTYFC CILEIIKADV SIFNPMEIIK
     EIREKRYGGN ISSIEYAYLL KALITYFFDN MMLLDTNNKR INFTNQYDNY LYKLNAPKGN
     MDKRIKRFLL FISILDDVKL DELCVQFDKV GIISDNGLKI KCKRFYDAKQ KNRYNDIPCL
     DKTSVNINGY DSKNVLGYIH ANQMIYKYGD EKERKIIMCQ APIPTTVDDM YDMIFRYKIG
     IIVILVNEKE IKEQNKCFPY FPTDAKEIKT SRFTILYINK KFDNENHIIE YDYTIFNDQN
     VSNNFKILQY INWPDKSIPT ESKTIHELYK KIINLDNNCQ IAIHCSTGIG RTGSLALAIY
     MIDMINSYVA YDPIKFLETL RSYRYKAVQT KMQFIFSLSI VYEHFKNKID EMDPDAYKNF
     TTMSKNILRQ NKEYKG
//