UniProt: A0A090LBD2

Database: UniProt
Entry: A0A090LBD2_STRRB

LinkDB:  A0A090LBD2_STRRB 
Original site:  A0A090LBD2_STRRB

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Ontology (2)   
   GO (2)   
Gene (1)   
   WORMBASE (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (15)   
   InterPro (8)   
   Pfam (3)   
   PROSITE (2)   
   SMART (2)   
All databases (19)   

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ID   A0A090LBD2_STRRB        Unreviewed;       327 AA.
AC   A0A090LBD2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Pre-mRNA-splicing factor RBM22 {ECO:0000256|ARBA:ARBA00020031};
DE   AltName: Full=RNA-binding motif protein 22 {ECO:0000256|ARBA:ARBA00030793};
GN   ORFNames=SRAE_2000174600 {ECO:0000313|EMBL:CEF67081.1,
GN   ECO:0000313|WBParaSite:SRAE_2000174600.1,
GN   ECO:0000313|WBParaSite:SRAE_2000174600.2,
GN   ECO:0000313|WormBase:SRAE_2000174600};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF67081.1};
RN   [1] {ECO:0000313|EMBL:CEF67081.1, ECO:0000313|Proteomes:UP000035682}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC   ECO:0000313|WBParaSite:SRAE_2000174600.1}, and ED321 Heterogonic
RC   {ECO:0000313|EMBL:CEF67081.1};
RA   Martin A.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_2000174600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (DEC-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SLT11 family.
CC       {ECO:0000256|ARBA:ARBA00007781}.
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DR   EMBL; LN609529; CEF67081.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A090LBD2; -.
DR   STRING; 34506.A0A090LBD2; -.
DR   EnsemblMetazoa; SRAE_2000174600.1; SRAE_2000174600.1; WBGene00261952.
DR   EnsemblMetazoa; SRAE_2000174600.2; SRAE_2000174600.2; WBGene00261952.
DR   WBParaSite; SRAE_2000174600.1; SRAE_2000174600.1; WBGene00261952.
DR   WBParaSite; SRAE_2000174600.2; SRAE_2000174600.2; WBGene00261952.
DR   WormBase; SRAE_2000174600; SRP10419; WBGene00261952; -.
DR   eggNOG; KOG0153; Eukaryota.
DR   OMA; RNNCQRN; -.
DR   OrthoDB; 929875at2759; -.
DR   Proteomes; UP000035682; Chromosome X.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.330; -; 1.
DR   Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR   InterPro; IPR039171; Cwc2/Slt11.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR048995; STL11/RBM22-like_N.
DR   InterPro; IPR032297; Torus.
DR   InterPro; IPR000571; Znf_CCCH.
DR   InterPro; IPR036855; Znf_CCCH_sf.
DR   PANTHER; PTHR14089; PRE-MRNA-SPLICING FACTOR RBM22; 1.
DR   PANTHER; PTHR14089:SF6; PRE-MRNA-SPLICING FACTOR RBM22; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   Pfam; PF21369; STL11_N; 1.
DR   Pfam; PF16131; Torus; 1.
DR   SMART; SM00360; RRM; 1.
DR   SMART; SM00356; ZnF_C3H1; 1.
DR   SUPFAM; SSF90229; CCCH zinc finger; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00723}.
FT   DOMAIN          161..188
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50103"
FT   DOMAIN          234..306
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   ZN_FING         161..188
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
SQ   SEQUENCE   327 AA;  36856 MW;  45DA2EA40FEA75EF CRC64;
     MAYRAAGNYN IRNQTDSGEF PIICETCLGP NPYGRMMKNK NSSECKVCTR VFTSFRWLPG
     RGARYKSTEI CQLCARLKNV CQTCLLDLQY GLPVQVRDQI LQVNDNAPKD GANREFYLQQ
     QERNLELTDG TTPGGVYGQI LDDGKNTVLT KLARTQPYYD RNKSHVCSFF VKGECKRGDE
     CPYRHEMPKD PDNPLSQQNI KDRYYGQNDP VASKLLNKAN ALPKLIPPED ITITTLYIGS
     LVDVDEDDLR DNFYQYGEIT NVTVLPEKKC GFVTFATRSA AEKAAAATFN NLIINDKRLS
     VKWGKPQTQK ANCTSTINLA PDLPAMF
//

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