ID   A0A090LCB8_STRRB        Unreviewed;       819 AA.
AC   A0A090LCB8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=RUN domain-containing protein {ECO:0000313|WBParaSite:SRAE_1000340800.1};
GN   ORFNames=SRAE_1000340800 {ECO:0000313|EMBL:CEF65155.1,
GN   ECO:0000313|WBParaSite:SRAE_1000340800.1,
GN   ECO:0000313|WormBase:SRAE_1000340800};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF65155.1};
RN   [1] {ECO:0000313|EMBL:CEF65155.1, ECO:0000313|Proteomes:UP000035682}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC   ECO:0000313|WBParaSite:SRAE_1000340800.1}, and ED321 Heterogonic
RC   {ECO:0000313|EMBL:CEF65155.1};
RA   Martin A.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_1000340800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (DEC-2020) to UniProtKB.
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DR   EMBL; LN609528; CEF65155.1; -; Genomic_DNA.
DR   STRING; 34506.A0A090LCB8; -.
DR   EnsemblMetazoa; SRAE_1000340800.1; SRAE_1000340800.1; WBGene00260025.
DR   WBParaSite; SRAE_1000340800.1; SRAE_1000340800.1; WBGene00260025.
DR   WormBase; SRAE_1000340800; SRP01213; WBGene00260025; -.
DR   OMA; QYYKRNA; -.
DR   OrthoDB; 126314at2759; -.
DR   Proteomes; UP000035682; Chromosome X.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.58.900; -; 1.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR025258; RH_dom.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   PANTHER; PTHR12326:SF12; PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1; 1.
DR   PANTHER; PTHR12326; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR   Pfam; PF13901; RH_dom; 1.
DR   Pfam; PF02759; RUN; 1.
DR   SMART; SM01175; DUF4206; 1.
DR   SMART; SM00593; RUN; 1.
DR   SUPFAM; SSF140741; RUN domain-like; 1.
DR   PROSITE; PS50826; RUN; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          36..173
FT                   /note="RUN"
FT                   /evidence="ECO:0000259|PROSITE:PS50826"
FT   DOMAIN          746..799
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   REGION          422..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          538..563
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        426..455
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   819 AA;  94492 MW;  0AB2DD7EF80AAFF2 CRC64;
     MSLDSSPEVK CAQLSHDLEH YVNLALKAEF RNVNNELSSD LTTSLCNVVE AIFINGLKDP
     FYIKGTRHNK YPQPNFWPLV YKFTDPVILK KITSLSLVKT EIGKARAWVR IHLNLKDLVK
     HISKFIGDSK AMGQFYHETA FLRDGNLIMN ACHMIMKLEM EEDLKINASI NTPFLDIWTN
     DPLVYAGIVQ GRREIATIES LTRSMMEKKI LEEKRKESIS EEVDESEEAI ILLNSSMEGC
     DTPTEQLNDN CFLNKTNDDD NISDDAQSSI YSQQSQYADS VGVGILDIYG LSPNTSGHFL
     SSTPKQEYMK FVLPDFSPAS TEHLPSAVQF QRRRARIQRK TSCGLLINNS KSEKVIDKLN
     ISKDSGKSFK SDEQIITKKI SIKENEIDNT IYSSSCPQRA LVNGFDDKLQ QTTMFTIGMS
     ENSLPEAVSE KDEINSIETP PSSDDRNEYT NEKLNDENEK KKIVYDSEVD DITMKRYCKS
     STSSVSGEKF FTDNEHSISH SFSSGNSFSG FRWRKPSSRQ SISPSSLEVC KNSFDACKSP
     ENEDKRDETQ EPSHKWETKT KSDDEERETF IRMIKQIPHE EGIDKQHYRC YMCFKSIENR
     ENIYTPCNLD KKYYCKACMK EGTKRLIPSR VILNGDFRAM KISPIHNKMI KKVYRDKIFD
     IETMNPLIYK YSKRFRIIKE KRTILSFVAL YLMYCQESVR QQLCDILAED DKNVTNIHSY
     SWKDLDETGS GELEKRITGY IEFAINHVYH CPLCSQKGFY CEICSTNQII YPFQTDETYR
     CSDCYSVYHR ECYDKTKKCP KCIRKKKLAE SIVNNPIYI
//