ID A0A090LDT5_STRRB Unreviewed; 627 AA.
AC A0A090LDT5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=ATP-binding cassette sub-family G member 2 {ECO:0000313|EMBL:CEF66288.1, ECO:0000313|WBParaSite:SRAE_2000095800.1};
GN ORFNames=SRAE_2000095800 {ECO:0000313|EMBL:CEF66288.1,
GN ECO:0000313|WBParaSite:SRAE_2000095800.1,
GN ECO:0000313|WormBase:SRAE_2000095800};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF66288.1};
RN [1] {ECO:0000313|EMBL:CEF66288.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000095800.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF66288.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000095800.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily.
CC {ECO:0000256|ARBA:ARBA00005814}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN609529; CEF66288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090LDT5; -.
DR STRING; 34506.A0A090LDT5; -.
DR EnsemblMetazoa; SRAE_2000095800.1; SRAE_2000095800.1; WBGene00261158.
DR WBParaSite; SRAE_2000095800.1; SRAE_2000095800.1; WBGene00261158.
DR WormBase; SRAE_2000095800; SRP02506; WBGene00261158; -.
DR eggNOG; KOG0061; Eukaryota.
DR OMA; NTPTDNR; -.
DR OrthoDB; 5354772at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03213; ABCG_EPDR; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48041:SF131; ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CEF66288.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 341..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..279
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 627 AA; 70711 MW; 824E0AA3E352F35C CRC64;
MSILKSHLSD PNFTNNCLEN GTTTSKSPFI DHSEPVTLTW NNIEVKTSSR HLLKKVSGVA
LPGECIALMG ASGAGKTTLL NTLLGRNSAN LTVSGEILVN GINVDRGITN ISSYVQQEDL
FMGRLTVYEH LIIQSYMRLP SNNSCSQRKQ RIKEIVDELE LNDCLHSKIG SAGLKKGISG
GQAKRLAFAT ELLTNPSLLF CDEPTTGLDS YMAAQVVRTL HRIACDTNTT IICTIHQPSS
EIFESFDRII FLALGEIAFQ GPPSDAINFF QYLGFKFPNQ SNPADLFIMY LAIEPGNEDE
SKNRINDICK KYNKSKYNDL VMKRIEWHKD NPHSTVNMPK PPSIFVITIA MIVRYFLDNL
RNNSIVFVKP IQKFSVGLIL GIFYFQTVHN QDGIANLKGL FYFVIAESIF PTTFMVNSAI
SKEYHLVSKE YHDGIYPIMS YYIARILAYI LFPLIDGSIM CTIIYLLVGL KFDIVAIFSL
YFILFMITFT SISFGSLISG IFIEYPVIQS MSTPILVSLS IFAGLFMNLT SLPNYISWLQ
HISWFKYGYE SFIITQFNNL ENIQCTIQKD GVLVDTEVCL RNGKEIIENM GFRSDNFSFN
MFILFVIGIT LFLLGYIAFT IRIIRGR
//
