ID A0A090LIL8_STRRB Unreviewed; 261 AA.
AC A0A090LIL8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Defective in cullin neddylation protein {ECO:0000256|RuleBase:RU410713};
GN ORFNames=SRAE_2000423600 {ECO:0000313|EMBL:CEF69588.1,
GN ECO:0000313|WBParaSite:SRAE_2000423600.1,
GN ECO:0000313|WBParaSite:SRAE_2000423600.2,
GN ECO:0000313|WormBase:SRAE_2000423600};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF69588.1};
RN [1] {ECO:0000313|EMBL:CEF69588.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000423600.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF69588.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000423600.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- FUNCTION: Neddylation of cullins play an essential role in the
CC regulation of SCF-type complexes activity.
CC {ECO:0000256|RuleBase:RU410713}.
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DR EMBL; LN609529; CEF69588.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090LIL8; -.
DR STRING; 34506.A0A090LIL8; -.
DR EnsemblMetazoa; SRAE_2000423600.1; SRAE_2000423600.1; WBGene00264465.
DR EnsemblMetazoa; SRAE_2000423600.2; SRAE_2000423600.2; WBGene00264465.
DR WBParaSite; SRAE_2000423600.1; SRAE_2000423600.1; WBGene00264465.
DR WBParaSite; SRAE_2000423600.2; SRAE_2000423600.2; WBGene00264465.
DR WormBase; SRAE_2000423600; SRP07839; WBGene00264465; -.
DR eggNOG; KOG3077; Eukaryota.
DR OMA; KEFFDGM; -.
DR OrthoDB; 169757at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR042460; DCN1-like_PONY.
DR InterPro; IPR005176; PONY_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12281:SF32; DCN1-LIKE PROTEIN; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14555; UBA_4; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 64..258
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
SQ SEQUENCE 261 AA; 30512 MW; 0DC8322514BDF51F CRC64;
MNGSRQQQAM IKRFTETAQT DRGTAIAYLS ESGWDINNAL SDYFNQQPYG MSYLSHHIGN
HTRNVAGTVD EIFKKFFDKV DDCGNNLGPN GVAKFLQYMN IDFSDRKVLI LAWMCEAKIQ
GEFSKEELET GILKLDIRKV DDISGRLTQW DRNLETAAYR EHFKNLYEFT YDYANDKPGR
KWLPIDVASA YWEILFKNPP TLMPLWLKFL QTTDSKKITK DTWNLVLEFM STMDERFKNY
TCEDCWPVLI DEFVEYAKNS V
//
