ID A0A090LK06_STRRB Unreviewed; 1606 AA.
AC A0A090LK06;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=LD29171p {ECO:0000313|EMBL:CEF68473.1, ECO:0000313|WBParaSite:SRAE_2000313000.1};
GN ORFNames=SRAE_2000313000 {ECO:0000313|EMBL:CEF68473.1,
GN ECO:0000313|WBParaSite:SRAE_2000313000.1,
GN ECO:0000313|WormBase:SRAE_2000313000};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF68473.1};
RN [1] {ECO:0000313|EMBL:CEF68473.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000313000.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF68473.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000313000.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; LN609529; CEF68473.1; -; Genomic_DNA.
DR STRING; 34506.A0A090LK06; -.
DR EnsemblMetazoa; SRAE_2000313000.1; SRAE_2000313000.1; WBGene00263350.
DR WBParaSite; SRAE_2000313000.1; SRAE_2000313000.1; WBGene00263350.
DR WormBase; SRAE_2000313000; SRP09000; WBGene00263350; -.
DR eggNOG; KOG0929; Eukaryota.
DR eggNOG; KOG2046; Eukaryota.
DR OMA; MENQVYE; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF375; LD29171P; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 504..693
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
SQ SEQUENCE 1606 AA; 183968 MW; 34D22C0661D46EBA CRC64;
MFLKTSIERI YNDKDIKKKD HINLKKACET ALEALKSYEE SDNNICNGSI LPTQRGFVLA
DNFFLPFELA CQAKSSRIVI TSLDCLQKLI AYGHLQGNIL DYENNDRMLI DRIVETICYP
FQGPHTDDAV QLQIIKAILA VVLSPSCHVH NGSLLLAIKT CFNIYLASKS NINQATARGI
LTQIINTVFE ALQKKLKEKH LYKVDDNDEN IIKDILESII NKISHEIDPN IKKPTSSNSS
IIEDNSECSD SISNEFLNEQ VSFSCPEEKD AFLLFRALCR LSMKALPDNP DFKSHELRSK
LLSLEMLLLI IQNFHINLPD KHCLVFAIRH YLCVALSKNS VSPFINVFEK SLAIFVLLVN
KFKTHLKLQI EVFFREIILN ILESGSSSFE HKWIVLNTVA KICEVPQSIV DIYVNYDCHL
TSYNIFENLI SILAKIAMGG TVIDPTNLTV VQIKEKEKCM KVLGLNSLVE ILQCLTEWYS
EVGSYAKVAD NEQDSDPETT SISQFTQLKQ QKSIIEHGID LFAKKATHGI KYLQEKNIVG
TEPAQIAKFF FGEDRLDKTV VGDYLGDGNS FNKEVMYSYI DLFDFTNMNI VAALRLLLEK
FRLPGEAQKI DRLMEKFASR FCECNSNLRL FASADTAYVL SYSIIMLTTD LHSPQVKNKM
TKEQYIAMNR GINDSADLPQ EYLSEIYDEI ASNEIKMKPT LSGKRNTNNN LVQQTARQRK
LIQNMELQSI SENAFALMEQ AARNHIEFTN ASHIEHVRPM FEITWTPCLA AFSIGLQASD
DIDIWSICLD GFKLGIRISC LFQMSLERNA YVQALARFTL LTAKNSIREM KPKNVESIKL
LMLVGEEDGD YLEECWYDVL KCISQLELAQ SLVTSNGKNN MAPNGQSIQL LLKNNGHVDE
KLIHSLQECL GEASSQNVIV AVDKIFQNSS RLNGDAIVHF VTQLCKVSLE ELTVPGRPRL
YMLQKIVEIS FYNMDRIRIE WSRIWLILGE HFNVAGCSSR ENVSHFALDA LKQLSMKFLE
RGELPNFRFQ KEFMKPFEVI MQKSSTLECR EMILACIANM VHSHSNRIKS GWKNIFSLFM
VAGRDNRSPI VECAFQTVTH IITEVCKNNF ISIVDFFQDA VKCLSEFSCN YNFPDISMES
IKLIRYCADH VSKNTHIFVE HCFDDLGSNT STPSMELSSP LKIRQNSMQK VWVRGWFPIF
SELYYIINDC KLDVRTRSLT VMFDIIKTYG SEFEDEWWKD LFNVLFKIFD FSKLRDNPNH
KNEWMTTTCN HALYAVVDVF TKFYNSLIPT QMLAFYELLY FFTEQLENDN LSRSAINCLE
ILILSCGEKF NTEMWDHTID LYERIFDITM PHCTTNLLNS ISPTHTKKEI NNEENIKKSN
ELTAKDKSDD QELNILLNQY IAQLELVNSI NSLLFKKVTG VTSLENIEEY GSTDVFGLLN
TDQLLKLVSS LIKSHKVSRE FSTNSVSRTV LWKALFKGKK KLNVVESETK TVNCVLSILF
KLIEPGFSEK EQTIVENIYK TLRETCMDCI TYYLLLDSAS HKTTWQPIIC LILNHSVEQT
KNNTIEGKEF SKSLAPIICK LIENEEPKCI RTLVSNFFEQ ALKNYL
//
