ID A0A090LK41_STRRB Unreviewed; 1635 AA.
AC A0A090LK41;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=ATP-binding cassette sub-family A member 2 {ECO:0000313|EMBL:CEF67910.1, ECO:0000313|WBParaSite:SRAE_2000257100.1};
GN ORFNames=SRAE_2000257100 {ECO:0000313|EMBL:CEF67910.1,
GN ECO:0000313|WBParaSite:SRAE_2000257100.1,
GN ECO:0000313|WormBase:SRAE_2000257100};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF67910.1};
RN [1] {ECO:0000313|EMBL:CEF67910.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_2000257100.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF67910.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_2000257100.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LN609529; CEF67910.1; -; Genomic_DNA.
DR STRING; 34506.A0A090LK41; -.
DR EnsemblMetazoa; SRAE_2000257100.1; SRAE_2000257100.1; WBGene00262782.
DR WBParaSite; SRAE_2000257100.1; SRAE_2000257100.1; WBGene00262782.
DR WormBase; SRAE_2000257100; SRP12375; WBGene00262782; -.
DR eggNOG; KOG0059; Eukaryota.
DR OMA; CIASASH; -.
DR OrthoDB; 2874848at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF269; ABC TRANSPORTER CED-7; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CEF67910.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 884..908
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1002..1020
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1092..1116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1128..1150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1162..1184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1233..1250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 509..750
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1301..1524
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1635 AA; 187468 MW; 6A7E89B47360CAAE CRC64;
MFFAHLFLLL YKNLLVLWRS KLWFILEFIF PIIIVLVEHY IIPENGNVII KPHIFHNVPV
LGNENDANLK VRMLPRIWPN CFERRKAIVM YTLDESILQN NSQLLLEEFG KRYSNKISLL
KMDSEKEILD VYKNKYKNDS YHCNPYIVSL HFQNISEKHG LQYKFIQPGV SNTYWMEKTQ
WIEGDVFGRS ADYFTLPKQP PYWSSGIITF QVALNEIFLN NFMKNINIPS LSLRRMPLPE
FHDNIVFSFI SKIPLLWLFV FSFTVIHSAR DVVAERESKV KAYLYANGVK AIPWFLSHFI
ITLSKMYINI AIMSIPLTVV LKPSTSIIFY IIVFSFGFSL CCFSLFITSF CKKSSTVTSV
TIFTLIIMKF LSNIYEPNRF QKTLCFLSSI NIISAFNFAI NTFCQIENSS KPLTAWSLFQ
MDQKSFTLGD AIFMLLLDGW IMLFLTFILD ALFPKDDSMP MSFKQFLSTY LPIKFNFKNE
YDRISLSTSE SESETIRESE LIWNENAILE VKKLVKSWNK SSGNAVDGVS FSVKKGNTTV
LLGHNGAGKS TTFSMLTGIT APTYGEIKLF GKHLYENLDE FRKNIGYCPQ DNPIFNNLTV
GEQLKFIVLL KKGIFGKISG KLSRANKNYC DVVSYLERLK LIDKVDEYCS NLSGGMKRKL
SVCMALCGGS EMVFLDEPTS GMDVEARQDV AILLNEEKKS RAILLTTHYM DEADSMGDRI
IIMGKGRVLC DGTSDFLKKK FGTGYQLTFT LENNSVFIKE NILEFVKRVI PNAVVNTKDT
SGQFSIILPI NDKHMFSQLF KNLEKNEKNL QIKSFGLSLN TLEQVFLKVG ELADGGEDET
DSAFKYAKLI STENDDDRVS GIKLIYNQMI ALFRKQIYYY KRNLFSFLMK QLPFILFFIG
TEMSLVFIKD FYFFEKTIKS DVSLLGPIKI PLQDVPFMNS SIMESYYNYL EPYKTFQIKK
LPSSENITSY IIKESLIEPP FGIGAKMNSL RNSMLLLFNG NAYHSIFYVV NVFFNVIANI
KKDFIKTSLV IFDVERSNIS TDDTFDQGYR TMVLIGFLFS THNNALCSYI EILVDERISR
FKHQQLLTKL NVITYWISFL IFNFITYSLV MLFYIGSAIV LSLFSQRIGY LLNLCTLYYF
AVIPFIYWMS FLFNKPSKAN SIMNACSILI PIAMTIIINL IGFVKGTHIS ENMDNLLKIL
VPGYNLLDSL LKLKTFENSS DIHEIETYLK KSYMLLIASA CLNLILLTII QSKIIRNFVY
NLWNSIYLRN VKNNYDENIR DDDVIGEIDW VNSAESIGLP LIANNLTKYY GKFKAVDDLS
FGVNEKDCFG LLGINGAGKT TTFDMLTGTT FPTSGEAYIK NISINNSPVI GYCPQFDALL
SDLSPYESMS VLSQLNGFID YKSRSTYALE SVDMLSHSNK KFKKLSGGQK RKISLSIAIM
ANTGMMFLDE PTSGIDPKAR RAIWNLLTEV RKQKQAILLT SHSMEECETL CTKIGFMNKG
KLSHIGTSQH LKSKFGSDYI LEIIFENPSL QMLDDINDVI VSRFDCSSAD IKTLRNTLRW
NIPKINLTWS VLYEFVENLH SKYSYNSSLE TMQSTTTSND NLKIPSIKDY SITQNSLEQV
FLRLSAMHEK SHRED
//
