ID A0A090M528_OSTTA Unreviewed; 1662 AA.
AC A0A090M528;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=OT_ostta10g01360 {ECO:0000313|EMBL:CEF99340.1};
OS Ostreococcus tauri.
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Ostreococcus.
OX NCBI_TaxID=70448 {ECO:0000313|EMBL:CEF99340.1, ECO:0000313|Proteomes:UP000009170};
RN [1] {ECO:0000313|Proteomes:UP000009170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OTTH0595 {ECO:0000313|Proteomes:UP000009170};
RX PubMed=16868079; DOI=10.1073/pnas.0604795103;
RA Derelle E., Ferraz C., Rombauts S., Rouze P., Worden A.Z., Robbens S.,
RA Partensky F., Degroeve S., Echeynie S., Cooke R., Saeys Y., Wuyts J.,
RA Jabbari K., Bowler C., Panaud O., Piegu B., Ball S.G., Ral J.-P.,
RA Bouget F.-Y., Piganeau G., De Baets B., Picard A., Delseny M., Demaille J.,
RA Van de Peer Y., Moreau H.;
RT "Genome analysis of the smallest free-living eukaryote Ostreococcus tauri
RT unveils many unique features.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11647-11652(2006).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family. RpoC1
CC subfamily. {ECO:0000256|ARBA:ARBA00007207}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CEF99340.1}.
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DR EMBL; CAID01000010; CEF99340.1; -; Genomic_DNA.
DR STRING; 70448.A0A090M528; -.
DR InParanoid; A0A090M528; -.
DR OrthoDB; 7998at2759; -.
DR Proteomes; UP000009170; Chromosome 10.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd02584; RNAP_II_Rpb1_C; 1.
DR CDD; cd02733; RNAP_II_RPB1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.1360.140; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 2.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR007073; RNA_pol_Rpb1_7.
DR InterPro; IPR038593; RNA_pol_Rpb1_7_sf.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR Pfam; PF05001; RNA_pol_Rpb1_R; 19.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
DR PROSITE; PS00115; RNA_POL_II_REPEAT; 11.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Plastid {ECO:0000256|ARBA:ARBA00022640};
KW Reference proteome {ECO:0000313|Proteomes:UP000009170};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 219..525
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 1531..1662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1531..1648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1662 AA; 184590 MW; 0BD02DEE4E970169 CRC64;
MSVHDRFPHS TAELCRVDAV QFGVLSPDEI RKMSVCAIES SDTYEKGRPK RGGLSDPRMG
TMDRGAVCET DGCDSVQTPG YFGHLELAKP VYHHGFINVV LRVLRCVGYS SSQLLLHKDE
DPKFAQLMRI KNPKNRLKKL TDACKTKSVC PYTGTAQPQY RLEGMKITAE FKHRDDELLP
EGGERKVVVT AERALQILKG ISDEDCRVLG LDPEHARPDW MILQVMPVPP PPVRPSVSFD
ASTRSEDDLT VKLMEIVRTN KNLERQEQNG APQHVILEFT ELLQYHIMTF MDNTVAGMPR
ALTRSGRSIK SISERLKGKA GRIRGNLMGK RVDFSARTVI TPDPNLMLDE LGVPWSIALN
MTYPETVTPY NIERLQRLVD NGPHPPPGET GARYIIREDG QRLDLRFLKK ASEKRLEYGY
KVERHMVNGD VVLFNRQPSL HKMSIMGHRV RIMPYSTFRL NLSVTPPYNA DFDGDEMNMH
LPQSYETKAE VKELMMVPKM IVSPQANKPV MAIVQDTLLG CRLITKRDTF IPKDVFMNII
MWLEDWDGKI PKPAILKPQP LWTGKQVFSM MLPKVNLLRT SAWARDADDV TFSVDDTGVR
IEQGELLTGT LCKKTMGSGG GGLIHVTWEE WGPIAARGLI SQTQTLVNYW LLHHGFTVGI
ADTIADDETM FTINNTITKA KADVKEVIKQ AQNNELELQP GMTMQQSFEQ KVNQILNKAR
DNAGNSAQNS LKDTNNVKMM VTAGSKGSFL NISQMIACVG QQNVEGKRIP YGFKGRTLPH
FSKDDFGPES RGFVENSYLR GLTPQEFFFH AMGGREGLID TAVKTSETGY IQRRLVKAME
DVVVKYDGTV RNSVGDVIQF LYGEDGMDAT MIESQVLDTL RLGAKEFAAV FQIDPDVSGF
NKGWLSNEQA SDLAHSTKVR EIIDAEWERL QKDRVELRKV FPTGDPHVHL PVNMKRIIWN
AQKQYGMYRP GGSEEELSVT HVIESVAELL PKLIVVAGTD PLSIEAQRNG TLLFFAHVRA
NLAAKRVLKD HKLTRAGFDW VIGEVESRFK MALAPPGDGI GVVAAQSIGE PATQMTLNTF
HFAGVSAKNV TLGVPRLKEI INIAKQIKTP SLTVALKPEF ASDRTKAKDV QASLEYTTLH
SVAAVTEVHY DPDPTDTVIE EDREFVRAYY EMPDEDVDPS RMSPWLLRIE LNREMMVDKK
LLMADVAERI NEDFGGDLSC IFNDDNSEKL VLRIRIMKAE GEKYDDSSIE DEVFLKRIET
QMLSNLALRG IPDIKKVFIR EAKSNAVNPR TQLFEKHTEW MLDTEGVNLL EVMAHPDVDF
TRTTSNHLIE VIQILGIEAV RNTLLRELRG VIEFDGSYVN YRHLAILVEV MTYRGHLVSI
TRHGINRAET GALMRCSFEE TVDILMEAAA FSERDNMTGP SENIMLGQFC PIGTGEFKLH
LDQEMLLDAV ELDLFETART PGHYGSMTPG REGTPGYGAK SPSFLLSPGG AMMSPFDTSM
AFSPYSDGGM AFSPGGMSPG GGVGYSPTSP AYSPTSPAYS PTSPAYSPTS PAYSPTSPAY
SPTSPAYSPT SPAYSPTSPA YSPTSPAYSP TSPAYSPTSP AYSPTSPAYS PTSPAYSPTS
PAYSPTSPAY SPTSPAYSPT SPAYSPTSPA YSPKEEDGEE EE
//
