ID A0A090MVX0_STRRB Unreviewed; 1009 AA.
AC A0A090MVX0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Protein SDA1 homolog {ECO:0000256|ARBA:ARBA00013636};
GN ORFNames=SRAE_1000144200 {ECO:0000313|EMBL:CEF63178.1,
GN ECO:0000313|WBParaSite:SRAE_1000144200.1,
GN ECO:0000313|WormBase:SRAE_1000144200};
OS Strongyloides ratti (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF63178.1};
RN [1] {ECO:0000313|EMBL:CEF63178.1, ECO:0000313|Proteomes:UP000035682}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC ECO:0000313|WBParaSite:SRAE_1000144200.1}, and ED321 Heterogonic
RC {ECO:0000313|EMBL:CEF63178.1};
RA Martin A.A.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SRAE_1000144200.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ISY1 family.
CC {ECO:0000256|ARBA:ARBA00007002}.
CC -!- SIMILARITY: Belongs to the SDA1 family.
CC {ECO:0000256|ARBA:ARBA00005783}.
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DR EMBL; LN609528; CEF63178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A090MVX0; -.
DR STRING; 34506.A0A090MVX0; -.
DR EnsemblMetazoa; SRAE_1000144200.1; SRAE_1000144200.1; WBGene00258048.
DR WBParaSite; SRAE_1000144200.1; SRAE_1000144200.1; WBGene00258048.
DR WormBase; SRAE_1000144200; SRP12167; WBGene00258048; -.
DR eggNOG; KOG2229; Eukaryota.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000035682; Chromosome X.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:InterPro.
DR Gene3D; 1.10.287.660; Helix hairpin bin; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR029012; Helix_hairpin_bin_sf.
DR InterPro; IPR009360; Isy1.
DR InterPro; IPR037200; Isy1_sf.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF06246; Isy1; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF140102; ISY1 domain-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000035682};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 71..442
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 559..703
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT REGION 528..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..588
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..603
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1009 AA; 117173 MW; 2A7807D99BC03E91 CRC64;
METIEDAEIV KVTNLDYNLT LLQEKVKKDP ESYRQEFSEQ FEHFKQNMKL LNIQPTQHRM
NLQPILELVV FLSKTAIYYK SDAEEFGRLM VDILTDQGPA LHHHIRESFC ESLLSLRNRK
HLDTIELLQL FFELCKIEDK NLRKFISTAI VSIIKKLSKS NDDLKLKTKM QVFLFAKLKD
SRAVVARLAQ MVLINVFRRG FWKDSKTANA IGECVFHRIP KIQVSGMKFF LGTTKDEEGV
AEDTDSEDDE AQTTKTLKEV MCAFRASKKT RKKEKMFEKA KKTISKDKKE KKEGKSKFCN
LYAIQCLYDP QQFVDRIFKM LESGKNEKFE VRVIRMALCA RIIGVHKLQT LGFYSFLHRY
LNPKQKEVTR ILLYAAQACH DLVPPDLVEN LVKVIANNFV TDKASTEAIV VGLNTIREIY
SNCPHAADAD LVQDLVQYRS YKNKNVAMAS KGIVTLFREI NPSILHRKDR GRPTEKSADI
DEAELEFGSL KAKTFIPGAE ILYGVEEGME MEDIDSDASE DWLDLDVDDK NESTNTEKNV
NVNNNEEEEE EELSGEEDDV SGEEDEIEVY DEEDEADDEE EEDLSDSEDV KKDDQNKEKE
VKLDELDPQE RIAKAQEISE NRIFTDADFK RIRVHQYRKA IMNKRGTKRK QTNADVQIEE
EFEEKKIRRE EGDGLPRLND IEHFHKKIKK QSKEERLAQV KEGREGREEY GKKVKTGEHV
GRTNRELAKK KNFSMIKQKY IKMARNSEKA QTTLARWLKF KELEERGPIS KRPANVKDCT
NVQDAERFLG EVSREITKNV TLIQNPGLGE GRIRDLNDEI NKLIKIKEAW EKRIRDLGGP
DHRRLRGNIE STGAGLASNR GYKYFGAAKD LPGVRELFAK EADNKHEKDF KKDNYVRNPG
AVYFGLLDDD NEKLIELEKI EEEIAKQKIE EEWKVRNSVM NKSHEFFKNA FYMDGDYNSV
IKEMETEDFI DDFMNNTKIK RFVVPNQEEM TTLLVEAKRK QLFEKLFGA
//
