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Database: UniProt
Entry: A0A090MY71_STRRB
LinkDB: A0A090MY71_STRRB
Original site: A0A090MY71_STRRB 
ID   A0A090MY71_STRRB        Unreviewed;       328 AA.
AC   A0A090MY71;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   26-FEB-2020, entry version 40.
DE   RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE            EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN   ORFNames=SRAE_2000134100 {ECO:0000313|EMBL:CEF66674.1,
GN   ECO:0000313|WormBase:SRAE_2000134100};
OS   Strongyloides ratti (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=34506 {ECO:0000313|EMBL:CEF66674.1, ECO:0000313|Proteomes:UP000035682};
RN   [1] {ECO:0000313|EMBL:CEF66674.1, ECO:0000313|Proteomes:UP000035682, ECO:0000313|WBParaSite:SRAE_2000134100}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ED321 {ECO:0000313|Proteomes:UP000035682,
RC   ECO:0000313|WBParaSite:SRAE_2000134100}, and ED321 Heterogonic
RC   {ECO:0000313|EMBL:CEF66674.1};
RA   Martin A.A.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SRAE_2000134100}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JAN-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:83421; EC=3.1.3.16;
CC         Evidence={ECO:0000256|SAAS:SAAS01116782};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC         COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:61977; EC=3.1.3.16;
CC         Evidence={ECO:0000256|RuleBase:RU004273,
CC         ECO:0000256|SAAS:SAAS01116780};
CC   -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC       {ECO:0000256|RuleBase:RU004273, ECO:0000256|SAAS:SAAS01017257}.
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DR   EMBL; LN609529; CEF66674.1; -; Genomic_DNA.
DR   STRING; 34506.g2734; -.
DR   EnsemblMetazoa; SRAE_2000134100; SRAE_2000134100; WBGene00261545.
DR   WBParaSite; SRAE_2000134100; SRAE_2000134100; WBGene00261545.
DR   WormBase; SRAE_2000134100; SRP09066; WBGene00261545; -.
DR   OMA; YLVMESR; -.
DR   Proteomes; UP000035682; Chromosome 2.
DR   GO; GO:0005694; C:chromosome; IEA:EnsemblMetazoa.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR   GO; GO:0031965; C:nuclear membrane; IEA:EnsemblMetazoa.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:EnsemblMetazoa.
DR   GO; GO:0070262; P:peptidyl-serine dephosphorylation; IEA:EnsemblMetazoa.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR   InterPro; IPR031675; STPPase_N.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF16891; STPPase_N; 1.
DR   PRINTS; PR00114; STPHPHTASE.
DR   SMART; SM00156; PP2Ac; 1.
DR   PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU004273, ECO:0000256|SAAS:SAAS01017252};
KW   Manganese {ECO:0000256|SAAS:SAAS01017251};
KW   Metal-binding {ECO:0000256|SAAS:SAAS01017255};
KW   Protein phosphatase {ECO:0000256|SAAS:SAAS01017274};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035682}.
FT   DOMAIN          118..123
FT                   /note="SER_THR_PHOSPHATASE"
FT                   /evidence="ECO:0000259|PROSITE:PS00125"
FT   REGION          301..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..321
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   328 AA;  37524 MW;  8B413909DF9E318B CRC64;
     MEELKIDAIL NRFLENRGTK PGKNVQLTEM EIKILCMKSR EIFLSQPMLL ELEAPLKICG
     DVHGQFYDLL RLFEYGGFPP ESNYLFLGDY VDRGKQSLET ICLLLAYKIK YPENFFLLRG
     NHESAAINRI YGFYDECKRR YNVKLWKTFT DCFNCLPVAA VIDEKIFCCH GGLSPDLQSL
     DQIKRMTRPT DVPDQGLLCD LLWSDPDKDV TGWGENDRGV SFTFGAEVVS KFLTKFDLDL
     ICRAHQVVED GYEFFAKRKL VTLFSAPNYC GEFDNAGSMM TVDETLMCSF QILKPSDKKK
     GYISNVNNSS RPVTPPRNNT PNGRKAKK
//
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