ID A0A090PYE2_9FLAO Unreviewed; 404 AA.
AC A0A090PYE2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=cysteine desulfurase {ECO:0000256|ARBA:ARBA00012239};
DE EC=2.8.1.7 {ECO:0000256|ARBA:ARBA00012239};
GN ORFNames=JCM19294_2587 {ECO:0000313|EMBL:GAK95805.1};
OS Nonlabens tegetincola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=323273 {ECO:0000313|EMBL:GAK95805.1, ECO:0000313|Proteomes:UP000029221};
RN [1] {ECO:0000313|EMBL:GAK95805.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 19294 {ECO:0000313|EMBL:GAK95805.1};
RA Nakanishi M., Meirelles P., Suzuki R., Takatani N., Mino S., Suda W.,
RA Oshima K., Hattori M., Ohkuma M., Hosokawa M., Miyashita K., Thompson F.L.,
RA Niwa A., Sawabe T., Sawabe T.;
RT "Draft Genome Sequences of Marine Flavobacterium Nonlabens Strains NR17,
RT NR24, NR27, NR32, NR33, and Ara13.";
RL Genome Announc. 2:e01165-14(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-
CC alanine; Xref=Rhea:RHEA:43892, Rhea:RHEA-COMP:14737, Rhea:RHEA-
CC COMP:14739, ChEBI:CHEBI:29917, ChEBI:CHEBI:35235, ChEBI:CHEBI:57972,
CC ChEBI:CHEBI:64428; EC=2.8.1.7;
CC Evidence={ECO:0000256|ARBA:ARBA00001357};
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. Csd subfamily.
CC {ECO:0000256|ARBA:ARBA00010447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAK95805.1}.
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DR EMBL; BBML01000001; GAK95805.1; -; Genomic_DNA.
DR RefSeq; WP_042276552.1; NZ_BBML01000001.1.
DR AlphaFoldDB; A0A090PYE2; -.
DR STRING; 319236.BST91_11760; -.
DR eggNOG; COG0520; Bacteria.
DR Proteomes; UP000029221; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0006534; P:cysteine metabolic process; IEA:InterPro.
DR CDD; cd06453; SufS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR010970; Cys_dSase_SufS.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR01979; sufS; 1.
DR PANTHER; PTHR43586; CYSTEINE DESULFURASE; 1.
DR PANTHER; PTHR43586:SF27; CYSTEINE DESULFURASE 1, CHLOROPLASTIC; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000029221};
KW Transferase {ECO:0000313|EMBL:GAK95805.1}.
FT DOMAIN 24..391
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 404 AA; 44122 MW; 24CF66AFF05D6825 CRC64;
MFDVQKIRQQ FPILQREVNG KPLIYFDNAA TSQKPQAVID AIVKYYSHYN ANIHRGVHAL
SQEATDLFEQ AREKTRAFFN IPQAKQVIFT SGNTHSINAV ASGAHVFVSK GDEVIVSAVE
HHSNIVPWQM LCEKVGAVLK VIPVLDDGTL DMKTYSNLLS NKTAFVVVNH ISNALGVTNP
VKEIIKQAHE FNALVLVDGA QSCGHMTVDV QALDADFYTM AGHKMCGPTG IGVLYGKEDL
LNQLPPYQGG GEMIDQVTFE HTTYAGLPHK FEAGTPNIAG GIALGAAIDY LNEIGMDNIA
TYENELLEYG TAQLKTIPGV TILGEVTDKA AVISFVVDKL HPYDIGTIVD KLGVAVRTGH
HCAQPVMDRF QIPGTIRASF AFYNTKEEID IMVQALQRAV NMLA
//
