ID A0A091B984_9GAMM Unreviewed; 920 AA.
AC A0A091B984;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Cation:proton antiporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=N787_06240 {ECO:0000313|EMBL:KFN48301.1};
OS Arenimonas metalli CF5-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Arenimonas.
OX NCBI_TaxID=1384056 {ECO:0000313|EMBL:KFN48301.1, ECO:0000313|Proteomes:UP000029393};
RN [1] {ECO:0000313|EMBL:KFN48301.1, ECO:0000313|Proteomes:UP000029393}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF5-1 {ECO:0000313|EMBL:KFN48301.1,
RC ECO:0000313|Proteomes:UP000029393};
RA Chen F., Wang G.;
RT "Genome sequencing of Arenimonas metalli.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFN48301.1}.
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DR EMBL; AVCK01000002; KFN48301.1; -; Genomic_DNA.
DR RefSeq; WP_052574990.1; NZ_AVCK01000002.1.
DR AlphaFoldDB; A0A091B984; -.
DR STRING; 1384056.N787_06240; -.
DR PATRIC; fig|1384056.3.peg.124; -.
DR eggNOG; COG1009; Bacteria.
DR eggNOG; COG2111; Bacteria.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000029393; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029393};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..21
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..617
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..704
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 745..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..800
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..826
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 846..866
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 886..908
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..109
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 125..412
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 607..670
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 680..768
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 779..902
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 920 AA; 97592 MW; BFE71E692CCC014F CRC64;
MLEALLAIPF VLALAIGLLP RERRRTAAWL AGLAPVAGLV LLALLTPPVL SGEGVRSLTE
WVPTLGLAVS LRLDGLAWMF AGLVLAIGGL IVLYARYYLS EEDSMPRFFC FLLLFMGSML
GLVVAGNLIL MAVFWELTSV SSFLLIGFWN HRSDAREGAR MALAITGTGG LALLGGVVLL
GRIAGSYELD VVLAAGPQIL ASPWYPAALG LVLLAVFTKS AQFPFQFWLP HAMAAPTPVS
AYLHSATMVK AGVFLLARLH PALAGSDLFF YVVSGIGAVT LLVGSWHAIF QHDIKGLLAY
STISHLGLIT LLFGLSTPMA VVAGLFHIIN HATFKASLFM AAGIIDHETG TRDMRRLGGL
FKLMPYTGAL AIIASLAMAG VPLLNGFLSK EMFFTEALEV EGHQFMRWGV AAAAVLAGAF
GVAYSLRFVD DTFFGPGPLR IETTPHEPPR WMRIPVEVLV VVCLAVGIVP ALTIAPVLHA
AATGVLGDDV PAYSLAIWHG LNVPLMMSLF GLAAGIALYF GIKRLIDLYG ISYDSLGRRV
FEWKTDRAIA WAGRLTATLE NGSLQRYLGL MVLAALVMGA TPFLAASLSP GGSQPMPPLG
WLVWAVGVAA TLATVALHRH RLLALVVMGA VGLAVSLAFL LLSAPDLALT QLLVEMVTIA
LMLLALNYLP EESPVERSRL RRWRDAAIAL AAGGGTAALV HAAITRPLDT VATEMLALSL
PEGGGTNVVN VILVDIRGFD TLGEITVFGV AGLIVHALLR HVRLRPERVV DGTPDPLLIP
NLVARLLLPL ALAVSLYLFL RGHNLPGGGF IAGLVLAVPM LLQYVLSGTD YVEQRLGFDY
PRVIGLGLAA ALLTGLGSWL LGYPYMTSHT DYVAVPLLGK LPLASAMAFD TGVYLVVAAG
TLLMLGMMGS VRAPGARRGG
//
