ID A0A091BKL2_9GAMM Unreviewed; 398 AA.
AC A0A091BKL2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=acetyl-CoA C-acyltransferase {ECO:0000256|ARBA:ARBA00024073};
DE EC=2.3.1.16 {ECO:0000256|ARBA:ARBA00024073};
GN ORFNames=N790_00645 {ECO:0000313|EMBL:KFN52311.1};
OS Arenimonas malthae CC-JY-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Arenimonas.
OX NCBI_TaxID=1384054 {ECO:0000313|EMBL:KFN52311.1, ECO:0000313|Proteomes:UP000029392};
RN [1] {ECO:0000313|EMBL:KFN52311.1, ECO:0000313|Proteomes:UP000029392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-JY-1 {ECO:0000313|EMBL:KFN52311.1,
RC ECO:0000313|Proteomes:UP000029392};
RA Chen F., Wang G.;
RT "Genome sequencing of Arenimonas malthae.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFN52311.1}.
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DR EMBL; AVCH01000001; KFN52311.1; -; Genomic_DNA.
DR RefSeq; WP_043799536.1; NZ_AVCH01000001.1.
DR AlphaFoldDB; A0A091BKL2; -.
DR STRING; 1384054.N790_00645; -.
DR PATRIC; fig|1384054.3.peg.114; -.
DR eggNOG; COG0183; Bacteria.
DR OrthoDB; 8951704at2; -.
DR Proteomes; UP000029392; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF8; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KFN52311.1}.
FT DOMAIN 9..267
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 275..396
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 95
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 354
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 384
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 398 AA; 41794 MW; 31E31CC5FD2447C9 CRC64;
MTKQIQDAYI VATTRTPVGK APRGVFRNTR PDEMLAHVLR AVVDQCPGID PTRIDDAIIG
CAMPEGEQGM NVARIGLLLA GLPNVIAAQT INRFCSSGLQ AVAMAADRIR LGEADLVLAG
GTESMSMVPM MGNKVAMSPK VFRDDNVAIA YGMGITAEKV AEEWKVSRED QDAFALASHQ
KAMAAQAAGE FTAEITPYQV VSRQPVLGSN TVKLRELLVK DDEGPRADTS AEGLAKLRPV
FRNGGSVTAG NSSQMSDGAG AVMLASAQAI KDYGLTPLAR FVGFSVAGVR PEVMGIGPIA
AIPKVLRQAG LTADQLDWIE LNEAFAAQAL AVIRTCELDP SKVNPLGGAI ALGHPLGATG
AIRTATIVHG LRRRQQKYGM VTMCIGTGMG AAGIFEAL
//
