ID A0A091C196_9ENTE Unreviewed; 685 AA.
AC A0A091C196;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=HD superfamily hydrolase {ECO:0000313|EMBL:KFN90465.1};
DE EC=3.1.4.- {ECO:0000313|EMBL:KFN90465.1};
GN ORFNames=TMU3MR103_1492 {ECO:0000313|EMBL:KFN90465.1};
OS Tetragenococcus muriaticus 3MR10-3.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Tetragenococcus.
OX NCBI_TaxID=1302648 {ECO:0000313|EMBL:KFN90465.1, ECO:0000313|Proteomes:UP000029381};
RN [1] {ECO:0000313|EMBL:KFN90465.1, ECO:0000313|Proteomes:UP000029381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3MR10-3 {ECO:0000313|EMBL:KFN90465.1,
RC ECO:0000313|Proteomes:UP000029381};
RA Chuea-nongthon C., Rodtong S., Yongsawatdigul J., Steele J.L., Liu X.-y.,
RA Speers J., Glasner J.D., Neeno-Eckwall E.C.;
RT "Genome sequence of Tetragenococcus muriaticus.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFN90465.1}.
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DR EMBL; JPVT01000152; KFN90465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091C196; -.
DR PATRIC; fig|1302648.3.peg.1457; -.
DR Proteomes; UP000029381; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KFN90465.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029381};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 240..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 463..606
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78115 MW; 4A023D8DC63861D1 CRC64;
MAEENIRANK TIEDTPATQQ KQELAAEAVG PEYTYQEEIA SEQQQLVNRL FDMVEKVRDD
SAEENERRRE EATDDDAVEE VTEDEKVAAM NEEIEQTEEE ELSFYQQIPR NFYRIVFSLD
QEELTQVQEE TLDIVEQRMT EQVRQADLNT ARQDAQEQVE TLDISNEQKE AVSDLMNEVI
VVNTFLNEQR TEELRQEAED SVQPVMIYQG EIIVREGSQI DSNAIQKLNV LGMTEQTQSF
FPFIAIILVA LLQIAVLYYF THSVKNKDKR ENQVVFYVVA MTLSLLFMKF FQLFQTEVMA
YIPLFFPAAF IPVVLNLFVN RRSGILAAAF QVVLAAFIFY EAAGTNVLPI ILLSYMFSGL
MGTLLPRRRI SHQGKQSMLW IVVFPFLISL TIFVLQGVNF ADSQTWIALA CSLTGSVLSL
LMGVGLYQFI ELMITDDSDI VLNELSNPNH TLLKKLLEEA PGTYHHSMMV ANLSANAVAE
IGGNTLLTRV ACYYHDIGKL KHANFFVENL PQEAENPHNF LLPEDSKQII FGHVTDGVKV
LEQEKMPQMV IDICQQHHGT TLMKFFYSKA KERNSEVTEE EFRYPGPNPQ TREAGVVSIA
DSCEAAVRAM ENPTNEKIDE FVSNLITDRM LDGQLDDTQL TLKELKIIKK SLINGLCSTF
HSRIKYPKMK SEAEKMKEEQ ERSGQ
//
