ID A0A091CML4_FUKDA Unreviewed; 555 AA.
AC A0A091CML4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Tudor and KH domain-containing protein {ECO:0000313|EMBL:KFO18230.1};
GN ORFNames=H920_20424 {ECO:0000313|EMBL:KFO18230.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO18230.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO18230.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO18230.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN125474; KFO18230.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091CML4; -.
DR STRING; 885580.ENSFDAP00000006578; -.
DR eggNOG; KOG2279; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22428; KH-I_TDRKH_rpt1; 1.
DR CDD; cd22429; KH-I_TDRKH_rpt2; 1.
DR CDD; cd20412; Tudor_TDRD2; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR047382; KH-I_TDRKH_rpt1.
DR InterPro; IPR047381; KH-I_TDRKH_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR047380; TDRD2-like_tudor.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22948:SF18; TUDOR AND KH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50084; KH_TYPE_1; 2.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 347..406
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 210..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 61032 MW; 9BB4A68AEE22092E CRC64;
MSTKQTSWTS LSTIQKVALG LGVPASAAVA YILYRRYRES REERLTFVGE DDIEIEMRVP
QEAVKLIIGR QGANIKQLRK QTGARIDVDT EDIGEERVLL ISGFPVQVCK AKAAIHQILT
ENTPVSEQLS VPQRAVGRII GRGGETIRSI CKASGAKITC DKESEGTLLL SRLIKISGTQ
KEHLILEKVS EDEELRKRIV HSAEARIPRK QPISVRREEM TESGGAGEPA LWRNASCGGR
QAAPLAVPPR KGGGDPAVVG PKEGSWEEPD NSFQKSGAQT SPEKSIFEIP SPDFSFHADE
YLEVYVSASE HPNHFWIQIV GSRSLQLDKL VSEMTQHYEN SPPEDLTVHA GDIVAAPLSA
NGSWYRARVL GTLENGNLDL YFVDFGDNGD CPLGDLRALR SDFLSLPFQA IECSLARIAP
SGEQWEEEAL DEFERLTYCA DWKPLVARIS SYVQTGISTW PKIYLYDTIN GQKLDIGLEL
VRKGYAIELP EDMEESGAVP GMLKDMATET DASLASLLTE PKKSPGEMAH TLSCLSLSEA
ASMSGDENLE DDYLL
//
