ID   A0A091CP21_FUKDA        Unreviewed;       326 AA.
AC   A0A091CP21;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=GDNF family receptor alpha-3 {ECO:0000313|EMBL:KFO19308.1};
GN   ORFNames=H920_19239 {ECO:0000313|EMBL:KFO19308.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO19308.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO19308.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO19308.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GDNFR family.
CC       {ECO:0000256|ARBA:ARBA00005961}.
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DR   EMBL; KN125101; KFO19308.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091CP21; -.
DR   STRING; 885580.ENSFDAP00000004406; -.
DR   eggNOG; ENOG502QWSW; Eukaryota.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR   InterPro; IPR016017; GDNF/GAS1.
DR   InterPro; IPR037193; GDNF_alpha.
DR   InterPro; IPR003438; GDNF_rcpt.
DR   InterPro; IPR003505; GDNF_rcpt_A3.
DR   PANTHER; PTHR10269:SF15; GDNF FAMILY RECEPTOR ALPHA-3; 1.
DR   PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR   Pfam; PF02351; GDNF; 2.
DR   PRINTS; PR01319; GDNFRALPHA3.
DR   PRINTS; PR01316; GDNFRECEPTOR.
DR   SMART; SM00907; GDNF; 3.
DR   SUPFAM; SSF110035; GDNF receptor-like; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFO19308.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          7..51
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          88..165
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          174..266
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
SQ   SEQUENCE   326 AA;  36232 MW;  62B580CB9ADF3B42 CRC64;
     MPSGKPAARE DCLEAAQQLR NSSLMGCSCP RRMKNQAACL NIYWTVHPAR SLGDYELDVS
     PYEDTVTSKP WRMNLSELNI LKPDSNTCLK FAMLCLLNDK CDRLRNAYGV ACSGSHCQRQ
     VCLQQLRAFF EKAEQPLVQG LLLCPCLPAD RDCGERRRNT IGPSCALPSP APNCLDLQRL
     CVGDLLCRSR LADFQTHCHP RGILGTCATE QFRCLHAYLG MIGTAMTPNF VSNVNTSVAL
     SCTCRGSGNL QEECEQLQRS FSSNACLEGA IAAKMRVHKQ LFFPDLVAPV PPVMEHQNKN
     SDLRPQPWVP FLFSCTLPLI LCCSLW
//