ID A0A091D4I3_FUKDA Unreviewed; 3024 AA.
AC A0A091D4I3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 12-AUG-2020, entry version 15.
DE SubName: Full=Centromere protein F {ECO:0000313|EMBL:KFO25418.1};
GN ORFNames=H920_13179 {ECO:0000313|EMBL:KFO25418.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO25418.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO25418.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO25418.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN123358; KFO25418.1; -; Genomic_DNA.
DR STRING; 885580.XP_010640824.1; -.
DR eggNOG; ENOG502QVMD; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT DOMAIN 74..377
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 2169..2308
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2351..2490
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2886..2927
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1762..1790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1909..1933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2801..3024
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 234..261
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 350..405
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 420..447
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 456..483
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 593..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 693..713
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 721..741
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 756..843
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 915..949
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 975..1068
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1098..1125
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1158..1178
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1194..1228
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1293..1320
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1363..1383
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1402..1422
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1460..1480
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1509..1529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1607..1659
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1684..1704
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1826..1895
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1970..2018
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2026..2172
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2180..2235
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2243..2316
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2390..2498
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2513..2694
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2699..2743
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2745..2779
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 200..227
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..343
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..551
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1918..1932
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2801..2822
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2834..2861
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2884..2898
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2913..2933
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2943..2966
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2994..3008
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3024 AA; 343271 MW; 963EEB668D38A8E9 CRC64;
MRRCAGLCLG DQDSEINEPS PNSEEPGPEK VQPRSSRGPA LAPQALGVWA AAGDSVHGKC
SLLNVGLIKE VNRMSWALEE WKEGLPTRAL QKIQELEGQL DKLKKEKQQR QFQLDTLEAA
LQKQKQKVET EKTEGTNLKR ENQRLMEICE NLEKTKQKIS HELQVKESQV NFQEGQLNSG
KKQIEKLEQE LKRCKTDLER SQQAAQSGDA SLSTPQRTFA TPLTPSQLYS GSKYEDLKEK
YNKEIEERNR LEAEVRALQA KRGSQAVPQT SMNHRDIARH QASSSVFSWQ QERTPNRLSS
HPQKTPSRRD FSASHIFGEE EVTPSRSVLQ TGHRDANSSW HNSSCGSPLL GQLKSQNQEL
RSKVNELELR LQGQEKEMKS QAHRFQELQL QLEKTKAELI EKDKVLNKNR DELVKTSAQH
DQAATKCTAL EQKLKKLTED MSCQRQNAES ARCSLEQRVK EKEKELQEEL SRQQRAFQTL
DQESTQMKAR LTQELQQAKN TLRGLEAELD KVSSAKLQLE KNLEEFKQKC SRMEQASEER
QVEEQALRSS SQEMKKENGF LRAQSEQRAR EVSHLEEELR KARVCLSQSQ NFTEEMRAKN
ASQETMMREL QEKINQQENS FTLEKLKLTL ADLEKQRDCS QDLLKKREHH IEQLNEKLSK
MEKESKALMS ALELTKKEYE ELNEEKTQFS RWRSENEKLL HQMESEKESL QSKVHHLEMC
LKTQQIKSHE YNERVRTLEM ERDNLGVEMR NLCSVVDSKT REAEMQKQAY EGLQQKAELS
EQKHKKEMEN LCMKTSQLTG QVEDLEQRLQ LLSSELLDKA QHYQELQAEY ENLRDLFKSK
ESARSQGDHQ SSCLAFEQQS AMSASFVNVM GEQGSNSLER SRCLLDADPS PKSPAILHSR
VISLEFSLES QKQMNSDLQK QCEELVHIKE EIEENLIKAE QMHESFVAET SQCICKLQED
TSVHQNVVAE TLVALENKEK ELQLWKARLE VEQVEIQELK KSNQLLEDSL KELQLLCETL
SSEKKEMSSI ISLSKKEIEE LTQENGTLKE MNEILNQEKM NLLQKNEKFS NCIEKQEKSI
SELSDQYKQE RLFLLQRCEE TGSAFEDLSE KYKAAQEKNL RLECLLNECN SVSESRKNEL
EQLKATFAKE HQEFFTKLAF AEEENQKLIL EFEVVQQALK SEIRDLRSSS KSETDALQQE
ITALKEGQNK MQKEVNDLFQ ENEQLMKLTK TKHEGQHLEL EPVRDPVNER ESEIDMCSFQ
LHTDLGVEDI APNNSNAQMV QLEALIGNTE LNPQESEKEK ESLQQEVQTL KGELKAGNLQ
GRSSQEMSGL MDCEADAEGK YSAVLCELSP RQGDHAHWRC SSLQAALSKL GELEKMCEML
QVEKLQLVSE LNDSRAECIT ATSRMAEEVE KLVNEMKILN DDNGLPQAES VGEMPANEFY
KWKNEQTLVS SNPLDTSNSY EQLTLSNKEV QTHFAELQEK FSSLLSEHKI LHDQRCQMSS
KMSELWSYVD TLKAENSALS VNLRNLQSDS AKEMKPEEHV LSLSFSCVTN SPSVTSFGES
SFYKDVLEQT GDTSFLSNLG ESVPTNASLE EECLTTKEAP ATAERSVEEL ETLCQGYLRS
LKNLQEEMES QAMVKDKEIQ ELGELLSSER TELDCLRKQY LSQNEQWQQK LTSVTLEMES
KLAAEKQQTE HLSLELEVAR LQLQGLELSS QSLLGADNEE AIQSQNGSYD IKESEEYTSE
ITEKTPKRDS HQICEEVVQQ DLSVESEETT EGPRVPQGAR EVPSEATDDT AVGVRGQGCL
QHTSELSSCG PHALAPMEFV ENQVSIQTLQ LQVKEASNEN LRLLHALEDR DRKVENLLNE
IKELDSRLDL QELQLRTKIK MCLQLEKIVE ELKKEKCNLS EKLESFSRAD QELGPRVETS
EALSSNLEMG TDDSPQEVLE ENVPMVGESR KDGFLAVEIK AEDAGIEHRA LAMEADLEVA
QNEKLCLERD KENCQKVIVH LEEELSVATS ERNRLHGELD TVTKENRTLA QMSEAMKEKV
QALEAEVRDK AAVLHTLSSQ LSELSADRGD LQKQLRRLEG DSQALSSAAR ELESQVGRLD
KEKESLARES ESLQAQLNEL EQERLSASRA LEVALMEKDE LAERLGSTQQ EVHQLRKGME
KLRVRIEADE KKQLHVLEKL KGCERDNDAL RDKVEGLQRE LQMSEENQEL VILDAENAKA
EAESLRAQVD EMAESLRGSR VDLTTLRSEK GDLTKQLQEQ QGQASKLEAR LSSLQSLVEE
KEQARAHMQE ESRTAVEMIQ AQVRELTEEV AALCQDQGTP KAEEQNLDAP GNEVPRLRYS
LGRLRARLDA DREKQLRVLG QLKGSECCVQ LLQGSVESLQ RELELSGRSQ EQAVREAENS
KAEVETLKAE IQEISQNLRD LKVDLVNTKS EKEDLTRGLQ KEQARVSELE IRNFSLENLL
QEKEHQNVQV KEESEVAVET LQAQLKLLNE KVVALCNDQE ACKTKEQSLS SRVDSLEVEK
AHLLQDLEGA KRNYVTLQSS VNGLMQEVED GKQELERKDE ELSRLQGQVQ DQEQLASQLS
QVEGERQLWQ KQKAELEQKV QGLQSQNHTL RDSLEALQNS CQELERELSS TKVEKISLVE
RVNTMTAKEA ELQAEMQDMV QKTTELKEEF SGEKNRLTAE LNVLLEEIKS SKTDHLKYVD
QLKKENERAQ GKIKLLLKSC RQLEEEKKML QKELSQGEAA QKQNTGALEA NVDELRAEIR
ELKETLEDRA KEADEYLDKY CSLLISHEKL EKAKEMLETQ VARLSSQHPK HGLSGSPLRS
SATPEPSPAP LVGEGKSSSG QSKASGKRQR CSGNWESGGG LTPSTPEAFP KKSRTVVGTG
GIHPAKDEEF EPEGLPEVVK KGFADIPTGK TSPYVLRRTT MATRTSPRLA AQKSALSPLS
AGKENLAESS KPTAGGSRSQ KVKVAQRSPA GSAEPTVKSA SVRHLSGRSP ADSPRDGPRT
RRSPLVPRPD ARPEPTNSEN CRVQ
//
