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Database: UniProt
Entry: A0A091D4I3_FUKDA
LinkDB: A0A091D4I3_FUKDA
Original site: A0A091D4I3_FUKDA 
ID   A0A091D4I3_FUKDA        Unreviewed;      3024 AA.
AC   A0A091D4I3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   12-AUG-2020, entry version 15.
DE   SubName: Full=Centromere protein F {ECO:0000313|EMBL:KFO25418.1};
GN   ORFNames=H920_13179 {ECO:0000313|EMBL:KFO25418.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO25418.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO25418.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO25418.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN123358; KFO25418.1; -; Genomic_DNA.
DR   STRING; 885580.XP_010640824.1; -.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT   DOMAIN          74..377
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2169..2308
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2351..2490
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2886..2927
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          321..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..566
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1762..1790
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1909..1933
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2801..3024
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          234..261
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          350..405
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          420..447
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          456..483
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          593..685
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          693..713
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          721..741
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          756..843
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          915..949
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          975..1068
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1098..1125
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1158..1178
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1194..1228
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1293..1320
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1363..1383
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1402..1422
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1460..1480
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1509..1529
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1607..1659
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1684..1704
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1826..1895
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1970..2018
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2026..2172
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2180..2235
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2243..2316
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2390..2498
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2513..2694
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2699..2743
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2745..2779
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        200..227
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..343
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..551
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1918..1932
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2801..2822
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2834..2861
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2884..2898
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2913..2933
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2943..2966
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2994..3008
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3024 AA;  343271 MW;  963EEB668D38A8E9 CRC64;
     MRRCAGLCLG DQDSEINEPS PNSEEPGPEK VQPRSSRGPA LAPQALGVWA AAGDSVHGKC
     SLLNVGLIKE VNRMSWALEE WKEGLPTRAL QKIQELEGQL DKLKKEKQQR QFQLDTLEAA
     LQKQKQKVET EKTEGTNLKR ENQRLMEICE NLEKTKQKIS HELQVKESQV NFQEGQLNSG
     KKQIEKLEQE LKRCKTDLER SQQAAQSGDA SLSTPQRTFA TPLTPSQLYS GSKYEDLKEK
     YNKEIEERNR LEAEVRALQA KRGSQAVPQT SMNHRDIARH QASSSVFSWQ QERTPNRLSS
     HPQKTPSRRD FSASHIFGEE EVTPSRSVLQ TGHRDANSSW HNSSCGSPLL GQLKSQNQEL
     RSKVNELELR LQGQEKEMKS QAHRFQELQL QLEKTKAELI EKDKVLNKNR DELVKTSAQH
     DQAATKCTAL EQKLKKLTED MSCQRQNAES ARCSLEQRVK EKEKELQEEL SRQQRAFQTL
     DQESTQMKAR LTQELQQAKN TLRGLEAELD KVSSAKLQLE KNLEEFKQKC SRMEQASEER
     QVEEQALRSS SQEMKKENGF LRAQSEQRAR EVSHLEEELR KARVCLSQSQ NFTEEMRAKN
     ASQETMMREL QEKINQQENS FTLEKLKLTL ADLEKQRDCS QDLLKKREHH IEQLNEKLSK
     MEKESKALMS ALELTKKEYE ELNEEKTQFS RWRSENEKLL HQMESEKESL QSKVHHLEMC
     LKTQQIKSHE YNERVRTLEM ERDNLGVEMR NLCSVVDSKT REAEMQKQAY EGLQQKAELS
     EQKHKKEMEN LCMKTSQLTG QVEDLEQRLQ LLSSELLDKA QHYQELQAEY ENLRDLFKSK
     ESARSQGDHQ SSCLAFEQQS AMSASFVNVM GEQGSNSLER SRCLLDADPS PKSPAILHSR
     VISLEFSLES QKQMNSDLQK QCEELVHIKE EIEENLIKAE QMHESFVAET SQCICKLQED
     TSVHQNVVAE TLVALENKEK ELQLWKARLE VEQVEIQELK KSNQLLEDSL KELQLLCETL
     SSEKKEMSSI ISLSKKEIEE LTQENGTLKE MNEILNQEKM NLLQKNEKFS NCIEKQEKSI
     SELSDQYKQE RLFLLQRCEE TGSAFEDLSE KYKAAQEKNL RLECLLNECN SVSESRKNEL
     EQLKATFAKE HQEFFTKLAF AEEENQKLIL EFEVVQQALK SEIRDLRSSS KSETDALQQE
     ITALKEGQNK MQKEVNDLFQ ENEQLMKLTK TKHEGQHLEL EPVRDPVNER ESEIDMCSFQ
     LHTDLGVEDI APNNSNAQMV QLEALIGNTE LNPQESEKEK ESLQQEVQTL KGELKAGNLQ
     GRSSQEMSGL MDCEADAEGK YSAVLCELSP RQGDHAHWRC SSLQAALSKL GELEKMCEML
     QVEKLQLVSE LNDSRAECIT ATSRMAEEVE KLVNEMKILN DDNGLPQAES VGEMPANEFY
     KWKNEQTLVS SNPLDTSNSY EQLTLSNKEV QTHFAELQEK FSSLLSEHKI LHDQRCQMSS
     KMSELWSYVD TLKAENSALS VNLRNLQSDS AKEMKPEEHV LSLSFSCVTN SPSVTSFGES
     SFYKDVLEQT GDTSFLSNLG ESVPTNASLE EECLTTKEAP ATAERSVEEL ETLCQGYLRS
     LKNLQEEMES QAMVKDKEIQ ELGELLSSER TELDCLRKQY LSQNEQWQQK LTSVTLEMES
     KLAAEKQQTE HLSLELEVAR LQLQGLELSS QSLLGADNEE AIQSQNGSYD IKESEEYTSE
     ITEKTPKRDS HQICEEVVQQ DLSVESEETT EGPRVPQGAR EVPSEATDDT AVGVRGQGCL
     QHTSELSSCG PHALAPMEFV ENQVSIQTLQ LQVKEASNEN LRLLHALEDR DRKVENLLNE
     IKELDSRLDL QELQLRTKIK MCLQLEKIVE ELKKEKCNLS EKLESFSRAD QELGPRVETS
     EALSSNLEMG TDDSPQEVLE ENVPMVGESR KDGFLAVEIK AEDAGIEHRA LAMEADLEVA
     QNEKLCLERD KENCQKVIVH LEEELSVATS ERNRLHGELD TVTKENRTLA QMSEAMKEKV
     QALEAEVRDK AAVLHTLSSQ LSELSADRGD LQKQLRRLEG DSQALSSAAR ELESQVGRLD
     KEKESLARES ESLQAQLNEL EQERLSASRA LEVALMEKDE LAERLGSTQQ EVHQLRKGME
     KLRVRIEADE KKQLHVLEKL KGCERDNDAL RDKVEGLQRE LQMSEENQEL VILDAENAKA
     EAESLRAQVD EMAESLRGSR VDLTTLRSEK GDLTKQLQEQ QGQASKLEAR LSSLQSLVEE
     KEQARAHMQE ESRTAVEMIQ AQVRELTEEV AALCQDQGTP KAEEQNLDAP GNEVPRLRYS
     LGRLRARLDA DREKQLRVLG QLKGSECCVQ LLQGSVESLQ RELELSGRSQ EQAVREAENS
     KAEVETLKAE IQEISQNLRD LKVDLVNTKS EKEDLTRGLQ KEQARVSELE IRNFSLENLL
     QEKEHQNVQV KEESEVAVET LQAQLKLLNE KVVALCNDQE ACKTKEQSLS SRVDSLEVEK
     AHLLQDLEGA KRNYVTLQSS VNGLMQEVED GKQELERKDE ELSRLQGQVQ DQEQLASQLS
     QVEGERQLWQ KQKAELEQKV QGLQSQNHTL RDSLEALQNS CQELERELSS TKVEKISLVE
     RVNTMTAKEA ELQAEMQDMV QKTTELKEEF SGEKNRLTAE LNVLLEEIKS SKTDHLKYVD
     QLKKENERAQ GKIKLLLKSC RQLEEEKKML QKELSQGEAA QKQNTGALEA NVDELRAEIR
     ELKETLEDRA KEADEYLDKY CSLLISHEKL EKAKEMLETQ VARLSSQHPK HGLSGSPLRS
     SATPEPSPAP LVGEGKSSSG QSKASGKRQR CSGNWESGGG LTPSTPEAFP KKSRTVVGTG
     GIHPAKDEEF EPEGLPEVVK KGFADIPTGK TSPYVLRRTT MATRTSPRLA AQKSALSPLS
     AGKENLAESS KPTAGGSRSQ KVKVAQRSPA GSAEPTVKSA SVRHLSGRSP ADSPRDGPRT
     RRSPLVPRPD ARPEPTNSEN CRVQ
//
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