ID A0A091D6R8_FUKDA Unreviewed; 629 AA.
AC A0A091D6R8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Motile sperm domain-containing protein 2 {ECO:0000313|EMBL:KFO18551.1};
GN ORFNames=H920_20061 {ECO:0000313|EMBL:KFO18551.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO18551.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO18551.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO18551.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN125361; KFO18551.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091D6R8; -.
DR STRING; 885580.ENSFDAP00000011345; -.
DR eggNOG; KOG0439; Eukaryota.
DR eggNOG; KOG1470; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR46384; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46384:SF1; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 604..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 196..350
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 438..556
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 71573 MW; 2E74D67768DCF422 CRC64;
MTDPGPQTPA SFPLSRKART WGEVLSDRPS GQTPPYLSKP STQQKPSAGT AFSHSKAPAS
ALHSGRPRPQ TVYLRAGLAG DETRPAAAEG TRAGPTVITS KIVVMAEILR TYRLWAFFTA
YLEKMACMPV TLIQVQNYKS DKYDPRDVER LQQDDNWVES YLHWRHNVVD DTLKMIDESF
QWRKEFSVHD LTESSIPRWL LEVGGIYLHG YDREGNKLFW IRVKYHIKDQ KTIMDKKKLI
AFWLEHYAKR ENGKPITVMF DLSETGLNSI DLDFVRFIIN CFKVYYPKYL SKIVIFDMPW
IMNAAFKIVK TWLGPEAVNL LKFTSKNEVQ EYVSVEYLPP HMGGTDPFKY SYPPLVDDDF
QTPLCENGPV ASEDETSSRE DVESDGKETL ETVTNEEQTA LPKKVNPTES SSKAEENEKV
DSKMKAFKKP LSVFKGSLLH ISPADELYFG STESGEKKSL IVLTNVTKNV VAFKVRTTAP
EKYRVKPSNS SCEPGASVDI VVSPHGGLTV SAQDRFLIMA AEMELSSGTG PTELTQFWKE
VPRNKVMEHR LRCHTMESSK PNTLILKDNA LNMSDKTSED IYLKLSRLLE SNKKFEDQLQ
RCIWLQQLLL ALIMLLFALV VTFFYSLYN
//
