ID A0A091D780_FUKDA Unreviewed; 135 AA.
AC A0A091D780;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|EMBL:KFO26338.1};
GN ORFNames=H920_12280 {ECO:0000313|EMBL:KFO26338.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO26338.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO26338.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO26338.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SEN15 family.
CC {ECO:0000256|ARBA:ARBA00006091}.
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DR EMBL; KN123200; KFO26338.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091D780; -.
DR STRING; 885580.ENSFDAP00000001411; -.
DR eggNOG; ENOG502S21U; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:InterPro.
DR Gene3D; 3.40.1350.10; -; 1.
DR InterPro; IPR018593; tRNA-endonuc_su_Sen15.
DR InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR InterPro; IPR036167; tRNA_intron_Endo_cat-like_sf.
DR PANTHER; PTHR28582; TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15; 1.
DR PANTHER; PTHR28582:SF1; TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15; 1.
DR Pfam; PF09631; Sen15; 1.
DR SUPFAM; SSF53032; tRNA-intron endonuclease catalytic domain-like; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000313|EMBL:KFO26338.1};
KW Hydrolase {ECO:0000313|EMBL:KFO26338.1};
KW Nuclease {ECO:0000313|EMBL:KFO26338.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 17..116
FT /note="tRNA-splicing endonuclease subunit Sen15"
FT /evidence="ECO:0000259|Pfam:PF09631"
SQ SEQUENCE 135 AA; 15182 MW; 255E8CA479D72A31 CRC64;
MMELDIGDAT QVYIAFLVYL DLMESKSWHE VNCVGLPELQ LICLVGTEIE GEGAQTVVPI
SVSASLSHNR IREILKASRK LQGDPDLPMS FTLAIVESDS TIVYYKLTDG FMLPDPQVSF
EVTDNKQWKR KKIMT
//
