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Database: UniProt
Entry: A0A091DAQ4_FUKDA
LinkDB: A0A091DAQ4_FUKDA
Original site: A0A091DAQ4_FUKDA 
ID   A0A091DAQ4_FUKDA        Unreviewed;       470 AA.
AC   A0A091DAQ4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   16-OCT-2019, entry version 29.
DE   RecName: Full=Protein C-ets-2 {ECO:0000256|PIRNR:PIRNR001698};
GN   ORFNames=H920_10521 {ECO:0000313|EMBL:KFO28147.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
OC   Hystricomorpha; Bathyergidae; Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO28147.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO28147.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO28147.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription factor. {ECO:0000256|PIRNR:PIRNR001698}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR001698,
CC       ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|PIRNR:PIRNR001698, ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; KN122816; KFO28147.1; -; Genomic_DNA.
DR   RefSeq; XP_010634843.1; XM_010636541.2.
DR   STRING; 885580.XP_010634843.1; -.
DR   Ensembl; ENSFDAT00000028004; ENSFDAP00000019833; ENSFDAG00000008873.
DR   GeneID; 104870780; -.
DR   CTD; 2114; -.
DR   OMA; RSWNSQS; -.
DR   OrthoDB; 526256at2759; -.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001712; P:ectodermal cell fate commitment; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; IEA:Ensembl.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR016311; Transform_prot_C-ets.
DR   InterPro; IPR027276; Transform_prot_C-ets-2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PIRSF; PIRSF501032; C-ets-2; 1.
DR   PIRSF; PIRSF001698; Transforming_factor_C-ets; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000028990};
KW   DNA-binding {ECO:0000256|PIRNR:PIRNR001698,
KW   ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR001698, ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW   Transcription {ECO:0000256|PIRNR:PIRNR001698};
KW   Transcription regulation {ECO:0000256|PIRNR:PIRNR001698}.
FT   DOMAIN       85    170       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      364    444       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION      270    292       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   470 AA;  52786 MW;  7C07A89CB4694CEE CRC64;
     MNDFGIKNMD QVAPVANSFR GTLKRQPAFD TFDGSLFAVF PSINEEQTLQ EVPTGLDSIS
     HDSTCCELPL LTPCSKAVMS QALKATFSGF QKEQRRLGIP RNPWLWTEQQ VCQWLLWATN
     EFSLVNVNLQ RFGMNGQVLC DLGKERFLEL APDFVGDILW EHLEQMIKEN QEKAEDQYEE
     NSHLNSVPQW INNNTLGFGV EQAAYGMQTP SYPKGGLLDA LCPSSTAPGV LSSEQDFQMF
     SKSRLSTVSG SYCSVGQDFA SNSLNLLASS TGKPKDHDSA EHGGDSFESS DSLMRSWNSQ
     SSLLDVQRVP SFESFEDDCS QTLCLGKPTI SFKDYIQERS DPVEQGKPVI PAAVLAGFTG
     SGPIQLWQFL LELLSDKSCQ SFISWTGDGW EFKLADPDEV ARRWGKRKNK PKMNYEKLSR
     GLRYYYDKNI IHKTSGKRYV YRFVCDLQNL LGFTPEELHA ILGVQPDTED
//
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