ID   A0A091DFP0_FUKDA        Unreviewed;       766 AA.
AC   A0A091DFP0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Potassium voltage-gated channel subfamily KQT member 3 {ECO:0000313|EMBL:KFO30969.1};
GN   ORFNames=H920_07607 {ECO:0000313|EMBL:KFO30969.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO30969.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO30969.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO30969.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KN122350; KFO30969.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091DFP0; -.
DR   STRING; 885580.ENSFDAP00000008376; -.
DR   eggNOG; KOG1419; Eukaryota.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:UniProt.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 6.10.140.1910; -; 2.
DR   InterPro; IPR020969; Ankyrin-G_BS.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR003948; K_chnl_volt-dep_KCNQ3.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   PANTHER; PTHR47735:SF11; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3; 1.
DR   PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   Pfam; PF11956; KCNQC3-Ank-G_bd; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01462; KCNQ3CHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   TRANSMEM        92..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        225..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          54..251
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   DOMAIN          341..543
FT                   /note="Potassium channel voltage dependent KCNQ C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03520"
FT   REGION          469..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          653..766
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        735..766
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   766 AA;  86011 MW;  C869241BBD265AD4 CRC64;
     MGRRRRVHCR SDPPAFLYLL PTASPARLPW RREGSEESDR AASQLTMKTK EDKETFAIFV
     FGAEFALRIW AAGCCCRYKG WRGRLKFARK PLCMLDIFVL IASVPVVAVG NQGNVLATSL
     RSLRFLQILR MLRMDRRGGT WKLLGSAICA HSKELITAWY IGFLTLILSS FLVYLVEKDV
     PEVDAQGEEM KEEFETYADA LWWGLITLAT IGYGDKTPKT WEGRLIAATF SLIGVSFFAL
     PAGILGSGLA LKVQEQHRQK HFEKRRKPAA ELIQAAWRYY ATNPNRIDLV ATWRFYESVV
     SFPFFRKEQL EAAASQKLGL LDRVRLSNPR GSNTKGKLFT PLNVDAIEES PSKEPKPVGL
     NNKERFRTAF RMKAYAFWQS SEDAGTGDPM GEDRGYGNDF LIEDMIPTLK AAIRAVRILQ
     FRLYKKKFKE TLRPYDVKDV IEQYSAGHLD MLSRIKYLQT RIDMIFTPGP PSTPKHKKSQ
     KGAAFTYPSQ QSPRNEPYVA RTSTAEMEDQ SMMGKFVKVE RQVHDMGKKL DFLVEMHVQH
     MERLQVRVSE YGPAKGTCSP AAGEKKEDSR YSDLKTIICN YSEAGAPEPP YSFHQLPIDK
     VGPYGFFAHD PVHLPRGGTA SAKAQAALPS SASSYAERPT VLPILTLLDS RGSFPSQAEP
     RGPCSERISP RQRCSLTRDS DTPLSLMSVN HEELERSPSG FSISQDRDDY TFGPGGGSSW
     MREKRYLAEG ETDTDTDPFT PSGSLPLSST GDGISDSIWT PSNKPT
//