ID   A0A091DG78_FUKDA        Unreviewed;       234 AA.
AC   A0A091DG78;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Defensin-7 {ECO:0000313|EMBL:KFO30082.1};
GN   ORFNames=H920_08516 {ECO:0000313|EMBL:KFO30082.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO30082.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO30082.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO30082.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; KN122504; KFO30082.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091DG78; -.
DR   STRING; 885580.ENSFDAP00000021363; -.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   InterPro; IPR016327; Alpha-defensin.
DR   InterPro; IPR002366; Alpha-defensin_N.
DR   PANTHER; PTHR11876; ALPHA-DEFENSIN 1; 1.
DR   PANTHER; PTHR11876:SF28; ALPHA-DEFENSIN 1; 1.
DR   Pfam; PF00879; Defensin_propep; 2.
DR   SMART; SM01418; Defensin_propep; 2.
PE   4: Predicted;
KW   Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW   Defensin {ECO:0000256|ARBA:ARBA00022940};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..234
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001872007"
FT   DOMAIN          1..45
FT                   /note="Alpha-defensin N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01418"
FT   DOMAIN          100..150
FT                   /note="Alpha-defensin N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01418"
FT   REGION          123..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        215..234
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   234 AA;  25409 MW;  E816FC52B01F9946 CRC64;
     MRTLTLLAAI LLLALQAQAE PLPGRADQAE EEEQDAVMTF SGEESSALQD AGGACAFSAE
     GCITFTKTTL SNISKRNTVR KDKMSKVKIK ELHPKGLPAM RTLALLAAIL LLALQAQAQP
     LPENAEEALE QQQPRQEDQD VAIPSAEAES SALQDAEQDL SALCVNQDLA DLCVNHKLGL
     RSICPNHNLF LSAPCFYYPS PHALCHGQDL DPIENKPSSL EERSSKKPDL KLQK
//