ID A0A091DN29_FUKDA Unreviewed; 994 AA.
AC A0A091DN29;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=B-lymphocyte antigen CD19 {ECO:0000313|EMBL:KFO33549.1};
GN ORFNames=H920_05086 {ECO:0000313|EMBL:KFO33549.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO33549.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO33549.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO33549.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN122083; KFO33549.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091DN29; -.
DR STRING; 885580.ENSFDAP00000000358; -.
DR eggNOG; ENOG502STG8; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0002322; P:B cell proliferation involved in immune response; IEA:InterPro.
DR GO; GO:0050864; P:regulation of B cell activation; IEA:InterPro.
DR CDD; cd17078; Ubl_SLD1_NFATC2ip; 1.
DR CDD; cd17079; Ubl_SLD2_NFATC2ip; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR042341; CD19.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR022617; Rad60/SUMO-like_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR16674; B-LYMPHOCYTE ANTIGEN CD19; 1.
DR PANTHER; PTHR16674:SF2; B-LYMPHOCYTE ANTIGEN CD19; 1.
DR Pfam; PF11976; Rad60-SLD; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..994
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001873261"
FT DOMAIN 20..98
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 176..274
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 921..992
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT REGION 329..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..418
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..769
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 994 AA; 108553 MW; 1E22B727431E2670 CRC64;
MPPPVLLSFL LLLFPKGGGP QKPLLVEVEE GADVVLPCLR GPSSAPSEWL VWSRGNQSVP
FLELSLGLPG LGVQMGPLGI LLLIFNVSDQ MGGFYLCQPG PPSKNAWQPG WTVSVEGSGK
LFRWNTSDLG DLSCGLGNGS SGGPRLSPHH PNNSQLYVWN QGHPEIWEAE PVCAPPRGSL
KESLTQDLTV APGSTLWLSC GAPTTHVTRG PISWTRVQPK KPNATLLNLY VREKPPVQEM
WVLGPVLSLS QATVQATGTY YCLRGNLTTE IQVKVIPQPA WQWLLRNGGW KLPVVPVVYL
TFCLGSLVAF LHIRRALVLR RKRKRMTDPT RRFFKVTPPP GNGTQNQYGN VLSLPTPTSG
TGRAQRWAAA LGGPVQPYGN PHAADVPEAG AASPPTAGVE EEEGEAYEEP DSEEGSEFYE
NDSSLGQDRL SRDGSGYENP EVRSVGPADE DSFSNGNSGS SWYLRGWADP ARCRAASRKR
APGALSCSAA ESYENADEEM APPAARPTDF LSPQGSAWDP SREATSLGSQ SYEDMRGILY
AAPQLRSLQP GPHHEEDADS YENMDNPDEP GLAWGGGDHM GVWSTRVEDY HSQDASLLYQ
RVQRVFYMGM GRERRRVNRD ELSQWRSPAG RTVDTVLVDL VSDSDEDVLE VATTRGAVDA
VEVQSPEPWV PAVPRGDSDS DERSAGRGGG VGAEGRRAPA VPAQGGESSF HPIPDPLSLL
KLYAEVAEEE ADMAESSSPH PEEPPFPSSP WKKLRSKDEK EEKKKVLLVE DTSPLPSPPP
RSKSRKHTQA LQKLREVNRR LQDLRSCLSP KQHQGQDHQS QDDEVLLVEG PVLPDNPRLF
SLKVRCRADV IRLPIKMSEP LQRVVDHMAS HLGVSPSRIL LLFGETELSP AATPRTLKLG
VADIIDCVVL ASSSEGEEVS QQLRLRVQGK EKHQMLEILL SQDSPLETLM SHYEKAMGLS
GHKLSFFFDG TKLSGKELPA DLGMESGDLI EVWG
//
