ID   A0A091DTM9_FUKDA        Unreviewed;       831 AA.
AC   A0A091DTM9;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Pleckstrin homology-like domain family B member 3 {ECO:0000313|EMBL:KFO33620.1};
GN   ORFNames=H920_04966 {ECO:0000313|EMBL:KFO33620.1};
OS   Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Fukomys.
OX   NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO33620.1, ECO:0000313|Proteomes:UP000028990};
RN   [1] {ECO:0000313|EMBL:KFO33620.1, ECO:0000313|Proteomes:UP000028990}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:KFO33620.1};
RA   Gladyshev V.N., Fang X.;
RT   "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT   African mole rats.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN122065; KFO33620.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091DTM9; -.
DR   STRING; 885580.ENSFDAP00000001640; -.
DR   eggNOG; ENOG502RF6E; Eukaryota.
DR   Proteomes; UP000028990; Unassembled WGS sequence.
DR   GO; GO:0050313; F:sulfur dioxygenase activity; IEA:InterPro.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR   CDD; cd14673; PH_PHLDB1_2; 1.
DR   CDD; cd07724; POD-like_MBL-fold; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR037810; PHLDB1/2/3_PH.
DR   InterPro; IPR044528; POD-like_MBL-fold.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR12156:SF22; PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 3; 1.
DR   PANTHER; PTHR12156; PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT   DOMAIN          723..826
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          264..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          454..482
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          598..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          364..391
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          422..452
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        285..304
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   831 AA;  92596 MW;  F4CCCFB505B6AB03 CRC64;
     MAGVALRVAG RQLSQRSGSG VPVLLRQMFE PKSCTYTYLL GDRETREAVL IDPVLETAPR
     DAQLVKELGL RLLYAVNTHC HADHITGSGV LRSLLPGCQS VISRLSGAQA DLHIEDGDSI
     RFGRFALETR ASPGHTPGCV TFVLNDHSMA FTGDALLIRG CGRTDFQQGC AKTLYHSVHK
     NIFTLPGECL VYPAHDYHGL TVSTVEEERT LNPRLTLSCE EFVKLMDNLN LPKPEQIAEA
     TAPRATAERV SGGLGAVGAE ELEPQVWFPG VTDSGSGLSG ERPQARPEEP SEQEAPEARE
     ELPSSRGAEQ QQAEEEEGGE GSSTESTRDE PEAKPPVQMP ATSPAPVRAR EGVRETALRL
     RGQQLEALTR VALMEQRVKE LQRQKKELRI REQQRLCRER ERVESLHQRL TEAQGQLDLQ
     PEDQHEQLLQ QVQELREQLE VAQRAYEDLE FQQLERESRQ EEEDQESPGA QAPDPRVQEL
     QASVAQHKRQ IQVLEEQLKS LGEQMAAESW ELSRKKEEAL QALTQERSRL LELSRCLQGA
     FGGDFSESKQ AHTKLLFTQK TDRQLVVLRD PSVHPAAASA SSCLLSVHSS LQGSIGLQRT
     GSLSRKRGER ASQRGSARPV SLHCTGALEA SALASAAGAS GRHPLYQLLN CGPSNGCRVL
     HPDIARMEQL LQQAVAERER LRQARAPPAS PPCPAAPHIL DLRQHLERWG HSPESCPHVR
     VSGGCCRGPL VKMGGRIKTW RKRWFCFDRQ ARRLAYYADK EQTKLKGVIY FQAIEEVYYD
     HLRSAFKSPN PRLTFCVKTY ERLFYMVAPS PEAMRIWMDV IVTAADENHA L
//