ID A0A091DTY5_FUKDA Unreviewed; 209 AA.
AC A0A091DTY5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN ORFNames=H920_12393 {ECO:0000313|EMBL:KFO26236.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO26236.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO26236.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO26236.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR EMBL; KN123228; KFO26236.1; -; Genomic_DNA.
DR RefSeq; XP_019065632.1; XM_019210087.1.
DR AlphaFoldDB; A0A091DTY5; -.
DR STRING; 885580.ENSFDAP00000020600; -.
DR Ensembl; ENSFDAT00000011726; ENSFDAP00000020600; ENSFDAG00000008319.
DR GeneID; 104873867; -.
DR CTD; 26291; -.
DR eggNOG; KOG3885; Eukaryota.
DR OMA; CQAYPIP; -.
DR OrthoDB; 4138817at2759; -.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005104; F:fibroblast growth factor receptor binding; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR035444; FGF15/19/21.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF81; FIBROBLAST GROWTH FACTOR 21; 1.
DR Pfam; PF00167; FGF; 1.
DR PIRSF; PIRSF037961; FGF-19_FGF-21; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Signal {ECO:0000256|RuleBase:RU049442}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT CHAIN 29..209
FT /note="Fibroblast growth factor"
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT /id="PRO_5005107071"
FT REGION 145..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..189
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 209 AA; 22524 MW; DA70163CA1410C6C CRC64;
MDWAGAESER PGLWVPALAV LLLGACQGRP IPDSSPLLQF GGQVRQRHLY TDDAQDTEVH
LEIRADGSVR GAAHRSPESL LELKALKPGV IQILGVRTSR FLCQRPDGTL YGSLHFDPEA
CSFRELLLED GYNIYQSEAH GLPLRMLPSD SSSRDPVPPG PARFLPLPGL HPAPPEPTGM
LPPEPPDVGS SDPLSMVGPL QGRSPSYAS
//
